1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl-

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1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- manufacturers

  • PREP inhibitor-1
  • PREP inhibitor-1 pictures
  • $195.00
  • 2026-04-20
  • CAS:2760543-16-4
  • Purity: 99.16%
  • Supply Ability: 10g
1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- Basic information
Product Name:1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl-
Synonyms:1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl-
CAS:2760543-16-4
MF:C22H28N4O2
MW:380.48
EINECS:
Product Categories:
Mol File:2760543-16-4.mol
1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- Structure
1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- Chemical Properties
Boiling point 696.6±55.0 °C(Predicted)
density 1.237±0.06 g/cm3(Predicted)
pka13.85±0.10(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- Usage And Synthesis
UsesPREP inhibitor-1 (compound 27a) is a highly potent prolyl oligopeptidase (PREP) inhibitor (IC50 < 1 nM).
References[1] Ptsi HT, et al. 2-Imidazole as a Substitute for the Electrophilic Group Gives Highly Potent Prolyl Oligopeptidase Inhibitors. ACS Med Chem Lett. 2021 Sep 17;12(10):1578-1584. DOI:10.1021/acsmedchemlett.1c00399
1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl- Preparation Products And Raw materials
Tag:1-Butanone, 1-[(2S)-2-[[(2S)-2-(1H-imidazol-2-yl)-1-pyrrolidinyl]carbonyl]-1-pyrrolidinyl]-4-phenyl-(2760543-16-4) Related Product Information
Prolyl endopeptidase inhibitor 2 Z-GLY-PRO-PNA eurystatin A (2S)-N-benzyl-2-[(2S)-2-(2-hydroxyacetyl)pyrrolidine-1-carbonyl]pyrrolidine-1-carboxamide FAP-IN-8 ZPP