- 1-Ethyl-2-methylindole
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- $11.00 / 1KG
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2021-08-25
- CAS:40876-94-6
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 100MT
- 1-Ethyl-2-methylindole
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- $1.00 / 1KG
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2019-08-06
- CAS:40876-94-6
- Min. Order: 1KG
- Purity: 95-99%
- Supply Ability: 100kg/week
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| | 1-Ethyl-2-methylindole Basic information |
| | 1-Ethyl-2-methylindole Chemical Properties |
| Boiling point | 266-267 °C (lit.) | | density | 1.02 g/mL at 25 °C (lit.) | | refractive index | n20/D 1.587(lit.) | | Fp | >230 °F | | storage temp. | Store at room temperature | | form | powder to crystal | | color | White to Light yellow | | InChI | 1S/C11H13N/c1-3-12-9(2)8-10-6-4-5-7-11(10)12/h4-8H,3H2,1-2H3 | | InChIKey | XMOWAIVXKJWQBJ-UHFFFAOYSA-N | | SMILES | CCn1c(C)cc2ccccc12 | | CAS DataBase Reference | 40876-94-6 | | EPA Substance Registry System | 1H-Indole, 1-ethyl-2-methyl- (40876-94-6) |
| WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 2933998090 | | Storage Class | 11 - Combustible Solids |
| | 1-Ethyl-2-methylindole Usage And Synthesis |
| Uses | 1-Ethyl-2-methylindole may be used in synthesis of hetrocyclic indole compounds. | | Synthesis Reference(s) | Synthesis, p. 617, 1979 DOI: 10.1055/s-1979-28783 | | Synthesis | Example 1 Synthesis of JWH4511-ethyl-2-methylindole: To a reaction vial containing 0.20 g (1.52 mmol) of 2-methylindole was added 6 mL of a DMSO-dissolved solution of 0.38 g (6.89 mmol) of KOH, followed by 0.24 mL (3.04 mmol) of ethyl iodide. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the reaction was quenched by the addition of 15 mL of water and extracted with ethyl acetate (2 x 15 mL). The organic phases were combined, washed sequentially with water (10 mL) and brine (20 mL), dried over anhydrous magnesium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography (eluent: ethyl ether/petroleum ether=0.5:9.5) to afford 0.20 g (83% yield) of the target compound N-ethyl-2-methylindole as a red oil. | | References | [1] Patent: WO2012/24670, 2012, A2. Location in patent: Page/Page column 43
[2] Synthesis, 1981, # 5, p. 389 - 390
[3] Organic Letters, 2017, vol. 19, # 17, p. 4680 - 4683 |
| | 1-Ethyl-2-methylindole Preparation Products And Raw materials |
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