2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride

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2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride Basic information
Product Name:2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride
Synonyms:2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride;(RS)-AMPA hydrochloride;4-Isoxazolepropanoic acid, α-amino-2,3-dihydro-5-methyl-3-oxo-, hydrochloride (1:1)
CAS:2922283-04-1
MF:C7H10N2O4.ClH
MW:222.63
EINECS:
Product Categories:
Mol File:2922283-04-1.mol
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride Structure
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride Chemical Properties
form Solid
color White to off-white
Safety Information
MSDS Information
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride Usage And Synthesis
Uses(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analogue and a potent and selective excitatory neurotransmitter L-glutamic acid agonist. (RS)-AMPA hydrobromide does not interfere with binding sites for kainic acid or NMDA receptors[1][2].
References[1] Hsli L, et al. Effects of the glutamate analogue AMPA and its interaction with antagonists on cultured rat spinal and brain stem neurones. Neurosci Lett. 1983 Mar 28;36(1):59-62. DOI:10.1016/0304-3940(83)90486-x
[2] Sommer B, et al. Flip and flop: a cell-specific functional switch in glutamate-operated channels of the CNS. Science. 1990 Sep 28;249(4976):1580-5. DOI:10.1126/science.1699275
2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)-propionic acid hydrochloride Preparation Products And Raw materials
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