ChemicalBook > Product Catalog >API >Specialty drugs >Dermatology drugs >Dersimelagon phosphate

Dersimelagon phosphate

Request For Quotation
Dersimelagon phosphate Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Dersimelagon phosphate Basic information
Product Name:Dersimelagon phosphate
Synonyms:Dersimelagon phosphate
CAS:2490660-87-0
MF:C36H45F4N3O5.H3O4P
MW:773.75
EINECS:
Product Categories:
Mol File:2490660-87-0.mol
Dersimelagon phosphate Structure
Dersimelagon phosphate Chemical Properties
Safety Information
MSDS Information
Dersimelagon phosphate Usage And Synthesis
UsesDersimelagon phosphate is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon phosphate shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon phosphate can be used for the research of skin pigmentation[1][2].
References[1] T. Suzuki, et al. Melanogenic effect of dersimelagon (MT-7117), a novel oral melanocortin 1 receptor agonist. Skin Health Dis. 2022; 2(1):e78.
[2] Erwin AL, et al. Porphyrias in the Age of Targeted Therapies. Diagnostics (Basel). 2021;11(10):1795. Published 2021 Sep 29. DOI:10.3390/diagnostics11101795
Dersimelagon phosphate Preparation Products And Raw materials
Tag:Dersimelagon phosphate(2490660-87-0) Related Product Information
BETA-MSH, HUMAN ALPHA-MSH Msg 606 JNJ-10229570 HS024 TFA Methanone, [(3S,4R)-4-(2,4-difluorophenyl)-1-(1,1-diMethylethyl)-3-pyrrolidinyl][(3R,5S)-4-hydroxy-3,5-diMethyl-4-phenyl-1-piperidinyl]-