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| | melarsonic acid Basic information |
| Product Name: | melarsonic acid | | Synonyms: | melarsonic acid;1,3,2-Dithiarsolane-4,5-dicarboxylic acid, 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]- | | CAS: | 37526-80-0 | | MF: | C13H13AsN6O4S2 | | MW: | 456.33 | | EINECS: | | | Product Categories: | | | Mol File: | 37526-80-0.mol |  |
| | melarsonic acid Chemical Properties |
| Boiling point | 850.4±75.0 °C(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 2.31±0.40(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | melarsonic acid Usage And Synthesis |
| Uses | Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently. | | in vivo | For acute infections produced by T. brucei brucei GVR, Potassium Melarsonyl exhibits trypanocidal activities. Potassium Melarsonyl (Trimelarsan) cures less than 50% mice at a dose of 25 μmol/kg for 4 consecutive days. At 60 μmol/kg, it cures all the mice in a chronic-infection model[1]. | | References | [1] Loiseau PM, et al. Contribution of dithiol ligands to in vitro and in vivo trypanocidal activities of dithiaarsanes and investigation of ligand exchange in an aqueous solution. Antimicrob Agents Chemother. 2000 Nov;44(11):2954-61. DOI:10.1128/AAC.44.11.2954-2961.2000 |
| | melarsonic acid Preparation Products And Raw materials |
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