2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride

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2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride Basic information
Product Name:2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride
Synonyms:SR 2640 HYDROCHLORIDE;SR2640HCl;2-[3-(2-Quinolylmethoxy)phenylamino]benzoic acid hydrochloride;2-[[3-[(Quinolin-2-yl)methoxy]phenyl]amino]benzoic acid;2-((3-(Quinolin-2-ylMethoxy)phenyl)aMino)benzoic acid hydrochloride;2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride
CAS:105350-26-3
MF:C23H18N2O3
MW:370.4
EINECS:
Product Categories:Prostanoid receptor and related
Mol File:105350-26-3.mol
2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride Structure
2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride Chemical Properties
Melting point >136°C (dec.)
Boiling point 580.3±45.0 °C(Predicted)
density 1.322±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 50 mg/mL, soluble
form solid
pka3.67±0.36(Predicted)
color yellow, powder with a tan cast
Stability:Hygroscopic
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
MSDS Information
2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride Usage And Synthesis
UsesSR 2640 Hydrochloride is a useful intermediate. It is a potent, selective LTD4 /LTE4 receptor antagonist.
DefinitionChEBI: 2-[3-(2-quinolinylmethoxy)anilino]benzoic acid is a member of quinolines.
Biological ActivityPotent and selective competitive leukotriene D 4 and E 4 receptor antagonist. Inhibits LTD 4 - but not histamine-induced guinea pig ileum and trachea contraction (pA 2 = 8.7). Also inhibits LTD 4 -attenuation of human PMN chemotaxis. Orally active in vivo .
2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride Preparation Products And Raw materials
Tag:2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride(105350-26-3) Related Product Information
2-[[3-(2-Quinolinylmethoxy)phenyl]amino]benzoic acid hydrochloride NA SR 2640 hydrochloride 2-(6-Methoxy-2-methyl-quinolin-4-ylamino)-benzoic acid hydrochloride p-(2-Quinolinylmethoxy)benzoic acid UOBOLPVJJAIUHQ-UHFFFAOYSA-N