SR 2640 hydrochloride

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SR 2640 hydrochloride manufacturers
SR 2640 hydrochloride Basic information
Product Name:SR 2640 hydrochloride
Synonyms:T23390
CAS:146662-42-2
MF:C23H19ClN2O3
MW:406.87
EINECS:
Product Categories:
Mol File:146662-42-2.mol
SR 2640 hydrochloride Structure
SR 2640 hydrochloride Chemical Properties
storage temp. Desiccate at RT
solubility Soluble to 50 mM in DMSO
form Powder
color Light yellow to yellow
Stability:Hygroscopic
Safety Information
MSDS Information
SR 2640 hydrochloride Usage And Synthesis
UsesSR 2640 Hydrochloride is a useful intermediate. It is a potent, selective LTD4 /LTE4 receptor antagonist.
in vivo

SR2640 inhibits the LTD 4-induced contractions of guinea-pig ileum in a concentration-dependent manner, with an IC50 of 3 nM[1]. SR2640 (1 mg/kg; IV; single dosage) specifically prevents the contractile responses of guinea-pig ileum and trachea to LTD4 and LTE4[1].

Animal Model:Guinea pigs (injected with LTD4 and LTE4)[1]
Dosage:1 mg/kg
Administration:IV; single dosage
Result:Specifically prevented the contractile responses of guinea-pig ileum and trachea to LTD4 and LTE4.
SR 2640 hydrochloride Preparation Products And Raw materials
Tag:SR 2640 hydrochloride(146662-42-2) Related Product Information
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