2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid

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2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid Basic information
Product Name:2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid
Synonyms:2-Ethoxy-5-[(4-methyl-1-piperazinyl;Benzoic acid, 2-ethoxy-5-[(4-methyl-1-piperazinyl)sulfonyl]-;Sildenafil Impurity 61;Sildenafil intermediate 2;5-(2-Hydroxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one;2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid
CAS:194602-23-8
MF:C14H20N2O5S
MW:328.39
EINECS:424-110-7
Product Categories:
Mol File:194602-23-8.mol
2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid Structure
2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid Chemical Properties
Melting point 198-199 °C
Boiling point 507.0±60.0 °C(Predicted)
density 1.319±0.06 g/cm3(Predicted)
vapor pressure 0Pa at 10.6℃
form Crystalline
pka3.79±0.10(Predicted)
LogP-2.37 at 20℃
Surface tension71.8mN/m at 1g/L and 16.5℃
Safety Information
MSDS Information
2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid Usage And Synthesis
Uses2-Ethoxy-5-(4-methyl-1-piperazinylsulfonyl)benzoic Acid is used as a reactant in the synthesis of Sildenafil Citrate (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
DefinitionChEBI: 2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylbenzoic acid is a 4-ethoxy-3-carboxybenzenesulfonamide in which the sulfonamide nitrogen is a member of a piperazine ring. It is a sulfonamide and a member of piperazines. It is functionally related to a benzoic acid.
2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid Preparation Products And Raw materials
Tag:2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]benzoic acid(194602-23-8) Related Product Information
Cichoric acid N,N-Dimethylallylamine Desethyl Carbodenafil 2-Ethoxybenzoyl chloride N-Des[2-(1-methyl-2-pyrrolidinyl)ethyl] Udenafil 1H-Pyrazolo[4,3-d]pyriMidine, 3-(2-Methylpropyl)- 1-Methyl-4-nitro-3-propyl-(1H)-pyrazole-5-carboxamide Propoxyphenyl ThiohoMosidenafil 5-chloro-2-ethoxybenzoyl chloride 4-(2-Ethoxy benzamido)-1-methyl-3-n-propyl pyrazole-5-carboxamide. Sildenafil Chlorosulfonyl Sulfosalicylic acid Sildenafil Impurity F 5-chloro-2-ethoxybenzoic acid KF31327 1-Methyl-4-nitro-3-propyl-1H-pyrazole-5-carboxylic acid 5-(2-Ethoxyphenyl)-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]-7-pyrimidinone 5-Dimethoxymethyl-benzo[1,3]dioxole