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| | Diethyl chlorophosphite Basic information |
| | Diethyl chlorophosphite Chemical Properties |
| Melting point | 25°C | | Boiling point | 153-155 °C (lit.)
56-57.5 °C/30 mmHg (lit.) | | density | 1.089 g/mL at 20 °C (lit.) | | refractive index | n20/D 1.434(lit.) | | Fp | 34 °F | | storage temp. | 2-8°C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | form | Liquid | | color | Clear colorless to yellow | | Water Solubility | Soluble in DMSO and chloroform. Reacts with water. | | Sensitive | Moisture Sensitive | | Merck | 14,3841 | | BRN | 1098392 | | Stability: | Air and Moisture Sensitive | | InChI | 1S/C4H10ClO2P/c1-3-6-8(5)7-4-2/h3-4H2,1-2H3 | | InChIKey | TXHWYSOQHNMOOU-UHFFFAOYSA-N | | SMILES | CCOP(Cl)OCC | | CAS DataBase Reference | 589-57-1(CAS DataBase Reference) | | EPA Substance Registry System | Phosphorochloridous acid, diethyl ester (589-57-1) |
| Hazard Codes | F,C | | Risk Statements | 11-14-34-37 | | Safety Statements | 16-26-36/37/39-45-7/8 | | RIDADR | UN 2924 3/PG 2 | | WGK Germany | 3 | | F | 10-21 | | TSCA | TSCA listed | | HazardClass | 3 | | PackingGroup | II | | HS Code | 29209085 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Flam. Liq. 2
Skin Corr. 1B
STOT SE 3 |
| | Diethyl chlorophosphite Usage And Synthesis |
| Chemical Properties | clear colorless to yellow liquid | | Uses | Diethyl Chlorophosphite is used in the synthesis of organophosphates and are considered anticholinesterase agents through observation in studies. | | Uses | In peptide synthesis. | | Uses | Diethyl chlorophosphite acts as a versatile phosphorylating agent for ester and lactone enolates, amines and alkenols. It is used in the synthesis of organophosphates and are considered anticholinesterase agents through observation in studies. |
| | Diethyl chlorophosphite Preparation Products And Raw materials |
| Raw materials | Ethyl phosphorodichloridite-->Ethanol-->Phosphorousacid, diethyl phenyl ester-->1,3,2-Diazaphosphol-4-ene, 2-ethoxy-1,3-dibutyl-4,5-dimethyl--->Phosphorous acid, 4,6-dimethyl-2-pyrimidinyl diethyl ester-->Phenyl phosphorodichloridite-->Phosphorocyanidous acid diethyl ester-->PYRUVONITRILE-->4,6-Dimethyl-2-hydroxypyrimidine hydrochloride-->Diethyl chlorothiophosphate-->Acetyl chloride-->Triethyl phosphite-->Diethyl phosphite | | Preparation Products | 1,3,2-Diazaphosphol-4-ene, 2-chloro-1,3-dibutyl-4,5-dimethyl--->Diphosphorus(III,V)oic acid tetraethyl ester |
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