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| | CTX-1211 (trifluoroacetate salt) Basic information |
| | CTX-1211 (trifluoroacetate salt) Chemical Properties |
| solubility | Ethanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml |
| | CTX-1211 (trifluoroacetate salt) Usage And Synthesis |
| Description | CTX-1211 is a peptide agonist of melanocortin receptors.1 It increases intracellular cAMP levels in cells expressing melanocortin receptor 1 (MC1R), MC3R, or MC4R (EC50s = 6.2, 3.9, and 2.7, nM, respectively). CTX-1211 (1 mg/kg) sensitizes male and female mice to reductions in food intake and body weight induced by liraglutide (Item No. 24727) but with a lower effect on food intake in female mice.2WARNING This product is not for human or veterinary use. | | References | [1] 4396607 Muramyl peptide derivatives and pharmaceutical compositions[J]. General Pharmacology-the Vascular System, 1984, 15 2: Page viii. DOI: 10.1016/0306-3623(84)90141-1
[2] NAIMA S DAHIR. Subthreshold activation of the melanocortin system causes generalized sensitization to anorectic agents in mice.[J]. Journal of Clinical Investigation, 2024, 134 14. DOI: 10.1172/jci178250 |
| | CTX-1211 (trifluoroacetate salt) Preparation Products And Raw materials |
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