4-(4-Cyanobenzyl)-1,2,4-triazole

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4-(4-Cyanobenzyl)-1,2,4-triazole Basic information
Product Name:4-(4-Cyanobenzyl)-1,2,4-triazole
Synonyms:4-((4H-1,2,4-TRIAZOL-4-YL)METHYL)BENZONITRILE;Benzonitrile, 4-(4H-1,2,4-triazol-4-ylmethyl)-;Letrozole Impurity 39;4-(4-Cyanobenzyl)-1,2,4-triazole
CAS:112809-27-5
MF:C10H8N4
MW:184.2
EINECS:
Product Categories:
Mol File:112809-27-5.mol
4-(4-Cyanobenzyl)-1,2,4-triazole Structure
4-(4-Cyanobenzyl)-1,2,4-triazole Chemical Properties
Melting point 144-147°C
Boiling point 412.1±55.0 °C(Predicted)
density 1.19±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly, Heated), Methanol (Slightly)
pka2.76±0.10(Predicted)
form Solid
color White to Pale Yellow
Safety Information
MSDS Information
4-(4-Cyanobenzyl)-1,2,4-triazole Usage And Synthesis
Uses4-(4-Cyanobenzyl)-1,2,4-triazole is an intermediate in the synthesis of Letrozole (L330100), an oral, non-steroidal, aromatase inhibitor generally used to treat breast cancer as a result of hormone response after surgery.
4-(4-Cyanobenzyl)-1,2,4-triazole Preparation Products And Raw materials
Raw materials4-(1H-1,2,4-Triazol-1-ylmethyl)benzonitrile-->1,2,4-Triazole-->4-Cyanobenzyl bromide
Tag:4-(4-Cyanobenzyl)-1,2,4-triazole(112809-27-5) Related Product Information
4-(4-Cyanobenzyl)-1,2,4-triazole 4,4'-(4H-1,2,4-Triazol-4-ylmethylene)bis benzonitrile Benzoic acid, 4-(4H-1,2,4-triazol-4-ylmethyl)- 3-fluoro-4-(4H-1,2,4-triazol-4-ylmethyl)benzonitrile 3-(4H-1,2,4-triazol-4-ylmethyl)aniline 4-[(4-Methoxyphenyl)methyl]-4H-1,2,4-triazole