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4-Iodobenzylamine hydrochloride manufacturers
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| | 4-Iodobenzylamine hydrochloride Basic information |
| | 4-Iodobenzylamine hydrochloride Chemical Properties |
| Melting point | 299-303 °C(lit.) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | Appearance | White to off-white Powder | | Water Solubility | Soluble in water. | | Sensitive | Light Sensitive | | BRN | 3691299 | | InChI | 1S/C7H8IN.ClH/c8-7-3-1-6(5-9)2-4-7;/h1-4H,5,9H2;1H | | InChIKey | GBJMURRFWZREHE-UHFFFAOYSA-N | | SMILES | Cl[H].NCc1ccc(I)cc1 | | CAS DataBase Reference | 59528-27-7(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 22-24/25-37-26 | | WGK Germany | 3 | | Hazard Note | Irritant/Light Sensitive | | HS Code | 29214990 | | Storage Class | 11 - Combustible Solids |
| | 4-Iodobenzylamine hydrochloride Usage And Synthesis |
| Uses | 4-Iodobenzylamine hydrochloride is used to prepare cyclic amide by reacting with methyl 4-bromomethyl-3-methoxycarbonylcinnamate in the presence of triethylamine. It is also used in pharmaceuticals, agrochemicals and dye industries. | | General Description | 4-Iodobenzylamine hydrochloride can be synthesized in three steps from 4-iodobenzoic acid. | | Synthesis | To a suspension of 4-iodobenzamide (11 g, 45 mmol) in THF (50 mL) was added BH3-THF (1M, 22.5 mL, ).
22.5 mmol). The resulting solution was heated to reflux overnight. The reaction was cooled in an ice bath and MeOH-HCl (60 mL) was added slowly and dropwise.
The resulting precipitate was filtered and dried to give 4-iodobenzylamine hydrochloride. White solid, yield 10.8 g, 88%. |
| | 4-Iodobenzylamine hydrochloride Preparation Products And Raw materials |
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