2-Amino-5-bromobenzaldehyde

2-Amino-5-bromobenzaldehyde Suppliers list

Company Name:	Wuhan Chemwish Technology Co., Ltd
Tel:	86-027-67849912
Email:	sales@chemwish.com

Company Name:	Nanjing Chemlin Chemical Co., Ltd
Tel:	025-83697070 13770331960
Email:	info@chemlin.com.cn

2-Amino-5-bromobenzaldehyde manufacturers

2-Amino-5-bromobenzaldehyde Basic information

Product Name:	2-Amino-5-bromobenzaldehyde
Synonyms:	Bromhexine Impurity 10;2-Amino-5-brombenzaldehyd;4-Bromo-2-formylaniline;aminobromobenzenecarbaldehyde;2-Amino-5-bromobenzaldehyde;2-Amino-5-bromobenzenecarbaldehyde;Benzaldehyde,2-aMino-5-broMo-;5-Bromoanthranilaldehyde, 4-Bromo-2-formylaniline
CAS:	29124-57-0
MF:	C7H6BrNO
MW:	200.03
EINECS:
Product Categories:
Mol File:	29124-57-0.mol

2-Amino-5-bromobenzaldehyde Chemical Properties

Melting point	75-77°
Boiling point	290.3±25.0 °C(Predicted)
density	1.673
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
pka	-0.35±0.10(Predicted)
form	Solid
color	Yellow
Sensitive	Air Sensitive
InChI	1S/C7H6BrNO/c8-6-1-2-7(9)5(3-6)4-10/h1-4H,9H2
InChIKey	VBYZWJMZASVGNB-UHFFFAOYSA-N
SMILES	Brc1cc(c(cc1)N)C=O
CAS DataBase Reference	29124-57-0

Safety Information

MSDS Information

2-Amino-5-bromobenzaldehyde Usage And Synthesis

Uses	Participate in synthesis and structure activity of novel camptothecin analogs.
Synthesis	20712-12-3 29124-57-0 General procedure for the synthesis of 2-amino-5-bromobenzaldehyde from 2-amino-5-bromobenzenemethanol: With reference to Example 286, 2-amino-5-bromobenzenemethanol (23.32 g) and activated manganese dioxide (58.5 g) were added to acetone (300 ml). The reaction mixture was stirred at room temperature for 17.5 hours and then filtered. The filtrate was concentrated under reduced pressure to give 2-amino-5-bromobenzaldehyde (16.41 g, 71% yield). The structure of the product was confirmed by 1H NMR (200 MHz, CDCl3): δ 6.10-6.20 (2H, br), 6.57 (1H, d, J=8.8 Hz), 7.38 (1H, dd, J=8.8,2.4 Hz), 7.59 (1H, d, J=2.4 Hz), 9.81 (1H, s).
References	[1] Organic Syntheses, 2013, vol. 90, p. 240 - 250 [2] ChemistryOpen, 2015, vol. 4, # 2, p. 107 - 110 [3] Patent: CN107304201, 2017, A. Location in patent: Paragraph 0061; 0065 [4] Patent: US6166006, 2000, A [5] Journal of Organic Chemistry, 2010, vol. 75, # 4, p. 1188 - 1196

2-Amino-5-bromobenzaldehyde Preparation Products And Raw materials

Raw materials	2-Nitro 5-bromo-benzaldehyde-->(2-Amino-5-bromophenyl)methanol-->Manganese dioxide-->Acetone
Preparation Products	3-Quinolinecarboxylic acid, 6-broMo-, Methyl ester-->6-Bromoquinoline-2-carboxylic acid-->6-Bromo-2-methylquinoline-->6-bromo-2-phenyl-4(1H)-Quinolinone

Tag:2-Amino-5-bromobenzaldehyde(29124-57-0) Related Product Information

BroMhexine Hydrochloride iMpurity DN-(2-AMino-5-broMobenzyl)-N-MethylcyclohexanaMine Dihydrochloride Bromhexine Impurity H N-Methylcyclohexylamine Bromhexine Impurity F (2R,3R,4R,5S)-6-((2,4-dibromo-6-((cyclohexyl(methyl)amino)methyl)phenyl)amino)hexane-1,2,3,4,5-pentaol 1-Methylamino-4-bromo anthraquinone 1-Amino-2,4-dibromoanthraquinone 5-Bromoisatin 2-Amino-2'-fluoro-5-bromobenzophenone 2-Amino-5-bromobenzoic acid Vat Blue 4B 2-Amino-3,5-dibromobenzoic acid 5-Bromoisatoic anhydride 1-Amino-4-bromo-2-methylanthraquinone 1-Amino-4-bromoanthraquinone-2-sulfonic acid sodium salt 2-Amino-5-bromobenzophenone 2-Acetamido-5-bromobenzoic acid 2-Amino-4,5-dibromobenzoic acid