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BOC Sciences |
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- CAY10397
-
- $213.00
-
2026-04-20
- CAS:78028-01-0
- Purity:
- Supply Ability: 10g
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| | CAY10397 Basic information |
| Product Name: | CAY10397 | | Synonyms: | CAY10397;CK47A;Ph CK 47A;DPHOCQNZARWEHS-UHFFFAOYSA-N;5-[[4-(ETHOXYCARBONYL)PHENYL]AZO]-2-HYDROXY-BENZENEACETIC ACID;5-[[4-(Ethoxycarbonyl)phenyl]azo]-2-hydroxybenzeneacetic acid, CK47A;5-[2-[4-(Ethoxycarbonyl)phenyl]diazenyl]-2-hydroxybenzeneacetic acid;CAY-10397,CAY10397 | | CAS: | 78028-01-0 | | MF: | C17H16N2O5 | | MW: | 328.32 | | EINECS: | | | Product Categories: | | | Mol File: | 78028-01-0.mol |  |
| | CAY10397 Chemical Properties |
| Boiling point | 578.0±50.0 °C(Predicted) | | density | 1.29±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | 0.1 M Na2CO3: 200 μg/ml; DMF: 35 mg/ml; DMSO: 25 mg/ml; Ethanol: 10 mg/ml | | form | solid | | pka | 4.05±0.10(Predicted) | | InChI | 1S/C17H16N2O5/c1-2-24-17(23)11-3-5-13(6-4-11)18-19-14-7-8-15(20)12(9-14)10-16(21)22/h3-9,20H,2,10H2,1H3,(H,21,22)/b19-18+ | | InChIKey | YYBSDOZYJSGLTH-VHEBQXMUSA-N | | SMILES | CCOC(=O)c1ccc(cc1)\N=N\c2ccc(O)c(CC(O)=O)c2 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | CAY10397 Usage And Synthesis |
| Uses | Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective inhibitor of 15-hydroxy PGDH with an IC50 of approximately 10 μM. CAY10397 acts to prolong the lifetime and activity of endogenously produced prostaglandins both in cell culture and in vivo.[Cayman Chemical] | | Definition | ChEBI: CAY10397 is a member of the class of azobenzenes that is azobenzene in which one of the phenyl groups is substituted at position 4 by an ethoxycarbonyl group, while the other is substituted by a carboxymethyl group at position 3 and a hydroxy group at position 4. It is a potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). It has a role as an EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor. It is a dicarboxylic acid monoester, an ethyl ester, a member of azobenzenes and a member of phenols. | | Biological Activity | Potent and selective inhibitor of 15-hydroxyprostaglandin dehydrogenase (15-hydroxy-PGDH). Acts to prolong the lifetime and activity of endogenously produced prostaglandins both in vitro and in vivo. |
| | CAY10397 Preparation Products And Raw materials |
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