- IKF 309
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- $1.00
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2019-12-26
- CAS:688046-61-9
- Min. Order: 1g
- Purity: ≥98%
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| | IKF 309 Basic information |
| Product Name: | IKF 309 | | Synonyms: | (5-Chloro-2-Methoxy-4-Methyl-3-pyridinyl)(2,3,4-triMethoxy-6-Methylphenyl)Methanone;3-(2,3,4-TriMethoxy-6-Methylbenzoyl)-5-chloro-2-Methoxy-4-Methylpyridine;IKF 309;Pyriofenone Solution;Methanone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)-;IKF 309（Pyriofenone）;Pyriofenone 100 μg/mL in Acetonitrile;Pyriofenone | | CAS: | 688046-61-9 | | MF: | C18H20ClNO5 | | MW: | 365.81 | | EINECS: | | | Product Categories: | Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 688046-61-9.mol |  |
| | IKF 309 Chemical Properties |
| Melting point | 91-94°C | | Boiling point | 519.8±50.0 °C(Predicted) | | density | 1.214±0.06 g/cm3(Predicted) | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | pka | -0.80±0.28(Predicted) | | form | Solid | | color | White to Off-White | | Henry's Law Constant | 5.3×103 mol/(m3Pa) at 25℃, Maniere et al. (2011) | | Stability: | Light Sensitive | | LogP | 4.469 (est) | | EPA Substance Registry System | Methanone, (5-chloro-2-methoxy-4-methyl-3-pyridinyl)(2,3,4-trimethoxy-6-methylphenyl)- (688046-61-9) |
| | IKF 309 Usage And Synthesis |
| Uses | IKF 309 is a fungicidal imidazole derivative use for controlling plant diseases caused by fungal plant pathogens. | | Uses | Pyriofenone is a fungicide. | | Definition | ChEBI: An aromatic ketone that is metrafenone in which the 3-bromo-6-methoxy-2-methylphenyl group is replaced by a 5-chloro-2-methoxy-4-methylpyridin-3-yl group. It is a fungicide developed for the control of powdery mildew in cereals and grape vines. | | Mechanism of action | Inhibits the formation of appressoria and the subsequent penetration of the hyphae in the plant cells | | Synthesis | Production of IKF 309 (Pyriofenone) begins with methyl 2-chloro-4-methyl nicotinate. An SNAr
(nucleophilic aromatic substitution) reaction introduces a methoxy group
to the pyridine ring. The pyridine ring is selectively chlorinated to
yield an intermediate compound which is subsequently hydrolysed to the
corresponding acid, then converted to an acid chloride. The acid
chloride reacts with 3,4,5-trimethoxy-toluene under Lewis acid catalysis
to form the final ketone structure of pyriofenone. The final stage is
purification and crystallisation. | | Pesticide Type | Fungicide |
| | IKF 309 Preparation Products And Raw materials |
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