| Company Name: |
Sigma-Aldrich |
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021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
DECYLUBIQUINONE manufacturers
- Decylubiquinone
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- $118.00
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2025-12-22
- CAS:55486-00-5
- Purity: 99.98%
- Supply Ability: 10g
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| | DECYLUBIQUINONE Basic information |
| Product Name: | DECYLUBIQUINONE | | Synonyms: | 2,3-DIMETHOXY-5-METHYL-6-DECYL-1,4-BENZOQUINONE;6-decylubiquinone;2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione;Decylubiquinone (2,3-Dmdb);DECYLUBIQUINONE;2,5-Cyclohexadiene-1,4-dione, 2-decyl-5,6-dimethoxy-3-methyl-;Decylubiquinone (2,3-Dmdb), MPTP inhibitor;Decylubiquinone(solution in ethanol) | | CAS: | 55486-00-5 | | MF: | C19H30O4 | | MW: | 322.44 | | EINECS: | | | Product Categories: | | | Mol File: | 55486-00-5.mol |  |
| | DECYLUBIQUINONE Chemical Properties |
| Boiling point | 452.9±45.0 °C(Predicted) | | density | 1.02±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO (up to 10 mg/ml) | | form | Neat yellow to orange colored oil. | | color | Yellow or orange | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. | | InChI | 1S/C19H30O4/c1-5-6-7-8-9-10-11-12-13-15-14(2)16(20)18(22-3)19(23-4)17(15)21/h5-13H2,1-4H3 | | InChIKey | VMEGFMNVSYVVOM-UHFFFAOYSA-N | | SMILES | CCCCCCCCCCC1=C(C)C(=O)C(OC)=C(OC)C1=O |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 10 - Combustible liquids |
| | DECYLUBIQUINONE Usage And Synthesis |
| Description | Decylubiquinone (55486-00-5) inhibits the Ca2+dependent mitochondrial permeability transition pore (MPTP) without inhibiting respiration.1Maximum effect on Ca2+retention capacity of rat liver mitochondria at 100 μM. Inhibits etoposide-induced apoptosis in in L929 cells at 5 μM via inhibition of cytochrome C release.2Delays rotenone-induced cardiac dysfunction in a zebrafish model of development and cardiovascular function.3Substrate for various quinone oxidoreductases.4,5 | | Uses | Decylubiquinone is inhibits the Ca2+-dependent mitochondrial permeability transition pore (MPTP) and also inhibits etoposide-induced apoptosis. | | Definition | ChEBI: 6-decylubiquinone is a member of the class of 1,4-benzoquinones that is 2,3-dimethoxybenzoquinone which has been substituted at positions 5 and 6 by decyl and methyl groups. It has a role as a cofactor. It is functionally related to a 6-decylubiquinol. | | General Description | Ubiquinone analog. | | References | [1] E FONTAINE P B F Ichas. A ubiquinone-binding site regulates the mitochondrial permeability transition pore.[J]. The Journal of Biological Chemistry, 1998, 273 40: 25734-25740. DOI:10.1074/jbc.273.40.25734
[2] N. KARPINICH. The Course of Etoposide-induced Apoptosis from Damage to DNA and p53 Activation to Mitochondrial Release of Cytochromec *[J]. The Journal of Biological Chemistry, 2002, 19 1: 16547-16552. DOI:10.1074/jbc.m110629200
[3] BRÍGIDA R PINHO. How mitochondrial dysfunction affects zebrafish development and cardiovascular function: an in vivo model for testing mitochondria-targeted drugs[J]. British Journal of Pharmacology, 2013, 169 5: 1072-1090. DOI:10.1111/bph.12186
[4] F420H2: quinone oxidoreductase from Archaeoglobus fulgidus. Characterization of a membrane-bound multisubunit complex containing FAD and iron-sulfur clusters
[5] VOLKER ZICKERMANN. Analysis of the Pathogenic Human Mitochondrial Mutation ND1/3460, and Mutations of Strictly Conserved Residues in Its Vicinity, Using the Bacterium Paracoccus denitrificans†[J]. Biochemistry Biochemistry, 1998, 37 34: 11792-11796. DOI:10.1021/bi9810555 |
| | DECYLUBIQUINONE Preparation Products And Raw materials |
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