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| | GSK-3 inhibitor 1 Basic information |
| Product Name: | GSK-3 inhibitor 1 | | Synonyms: | GSK-3 inhibitor 1;3-(9-Fluoro-1,2,3,4-tetrahydropyrrolo[3,2,1-jk][1,4]benzodiazepin-7-yl)-4-imidazo[1,2-a]pyridin-3-yl-1H-pyrrole-2,5-dione monohydrochloride;PubChem ID: 78357782;GSK 3 inhibitor 1,GSK3 inhibitor 1;3-(9-fluoro-1,2,3,4-tetrahydro-[1,4]diazepino[6,7,1-hi]indol-7-yl)-4-(imidazo[1,2-a]pyridin-3-yl)-1H-pyrrole-2,5-dione hydrochloride | | CAS: | 603272-51-1 | | MF: | C22H17ClFN5O2 | | MW: | 437.86 | | EINECS: | | | Product Categories: | | | Mol File: | 603272-51-1.mol |  |
| | GSK-3 inhibitor 1 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Powder | | color | Yellow to orange |
| | GSK-3 inhibitor 1 Usage And Synthesis |
| Uses | GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny)[1][2]. | | IC 50 | GSK-3 | | References | [1] SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: III. 20170252449 A1
[2] Christopher Loose, et al. 1h-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells. Patent WO2018125746A1. |
| | GSK-3 inhibitor 1 Preparation Products And Raw materials |
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