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| Product Name: | MOUSE IL-5 | | Synonyms: | Rabbit Interleukin 5 (IL5)ELISA Kit;INTERLEUKIN 5, MOUSE;IL-5 MURINE;MOUSE IL-5;INTERLEUKIN-5, MOUSE, RECOMBINANT;INTERLEUKIN 5 MURINE;IL-5, MOUSE;MOUSE INTERLEUKIN 5 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![MOUSE IL-5 Structure]() |
| | MOUSE IL-5 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | biological source | mouse |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | MOUSE IL-5 Usage And Synthesis |
| Biological Activity | Interleukin-5 exhibits activity on eosinophils, B cells, and thymocytes. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity.', 'Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity. | | Description | Interleukin-5 Mouse Recombinant produced in E.Coli is a dimeric, non-glycosylated polypeptide chain containing 2 x 113 amino acids forming a disulfide linked homodimer and having a molecular mass of 26.2 kDa.
The Mouse IL-5 is purified by proprietary chromatographic techniques. | | Source | Escherichia Coli | | Background | The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. |
| | MOUSE IL-5 Preparation Products And Raw materials |
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