| Company Name: |
ACROBiosystems Gold
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| Tel: |
13121935750 |
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jiaxin.zhao@acrobiosystems.com |
| Products Intro: |
Product Name:PD-1
Purity:99% Package:100ug/;500ug/;1000ug/
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| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
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Product Name:α-Synuclein E46K human
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Shanghai Huzhen Industrial Co., LTD
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021-60345367 13916550749 |
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sales@shzbio.com |
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Product Name:PD-1
Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:Programmed cell death protein 1; CD279; CD279 antigen; hPD 1; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Protein PD 1; Protein PD-1; SLEB2; Syste
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| Company Name: |
Biolab Reagents
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65279366 18108604356 |
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products@biolabreagent.com |
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Product Name:PD-1
Purity:95% SDS-PAGE Package:1mg;100ug
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| | non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) Basic information |
| Product Name: | non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) | | Synonyms: | Anti-SNCA antibody produced in goat;CD279 (human): FC (human);PD1;non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor);α-Synuclein E46K human;PARK4;NACP (Non-a-beta component of Alzheimer disease amyloid, precursor);non A4 component of amyloid precursor | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) Structure]() |
| | non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) Chemical Properties |
| storage temp. | -20°C | | form | lyophilized powder | | biological source | human |
| WGK Germany | WGK 2 | | Storage Class | 10 - Combustible liquids |
| | non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) Usage And Synthesis |
| Uses | Programmed Death-1 (PD-1, CD279) is a type I transmembrane protein belonging to the CD28/CTLA-4 family of immunoreceptors that mediate signals for regulating immune responses. Members of the CD28/CTLA-4 family have been shown to either promote T cell activation (CD28 and ICOS) or downregulate T cell activation (CTLA-4 and PD-1). CD279 is expressed on activated T-cells, B-cells, myeloid cells and on a subset of thymocytes. In vitro, ligation of CD279 inhibits TCR-mediated T-cell proliferation and production of IL-1, IL-4, IL-10 and IFN-γ. In addition, CD279 ligation also inhibits BCR mediated signaling. CD279 deficient mice have a defect in peripheral tolerance and spontaneously develop autoimmune diseases. | | Biochem/physiol Actions | Among the familial mutations of α-synuclein in Parkinson′s disease, E46K has the greatest potential to aggregate. This mutation is a 188G-A tran-sition resulting in a Glu46-to-Lys (E46K) substitution in the amino-terminal region of the protein. |
| | non A4 component of amyloid precursor, PARK1, PARK4, PD1, NACP (Non-a-beta component of Alzheimer disease amyloid, precursor) Preparation Products And Raw materials |
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