- 1-azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid
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2026-07-24
- CAS:1644163-57-4
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- N3-PEG10-PA
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2026-07-24
- CAS:1644163-57-4
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- azido-PEG10-Acid
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2025-06-07
- CAS:1644163-57-4
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Azido-PEG10-acid Basic information |
| Product Name: | Azido-PEG10-acid | | Synonyms: | Azido-PEG10-acid;Azido-PEG11-acid;N3-PEG10-COOH;Azido-PEG10-tBu Ester;N3-PEG10-CH2CH2COOH/Propanoic acid, 3-[(29-azido-3,6,9,12,15,18,21,24,27-nonaoxanonacos-1-yl)oxy]-;1-Azido-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid;N3-PEG10-PA | | CAS: | 1644163-57-4 | | MF: | C23H45N3O12 | | MW: | 555.62 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1644163-57-4.mol |  |
| | Azido-PEG10-acid Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF |
| | Azido-PEG10-acid Usage And Synthesis |
| Description | Azido-PEG10-acid is a water soluble PEG compound containing an azide group with a terminal carboxylic acid. The azide (N3) group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. | | Uses | Azido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG10-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG10-acid Preparation Products And Raw materials |
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