- 1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid
-
-
2026-07-24
- CAS:1670249-37-2
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- N3-PEG9-PA
-
-
2026-07-24
- CAS:1670249-37-2
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- azido-PEG9-Acid
-
-
2025-06-07
- CAS:1670249-37-2
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
|
| | Azido-PEG9-acid Basic information |
| Product Name: | Azido-PEG9-acid | | Synonyms: | 3-[2-[2-[2-[2-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid;Azido-PEG9-acid;N3-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxatriacontanoic acid, 30-azido-;Azido-PEG9-CH2CH2COOH;1-azido-3,6,9,12,15,18,21,24,27-nonaoxatriacontan-30-oic acid;N3-PEG9-PA;N3-PEG9-CH2CH2COOH;N3-PEG9-COOH | | CAS: | 1670249-37-2 | | MF: | C21H41N3O11 | | MW: | 511.57 | | EINECS: | | | Product Categories: | peg | | Mol File: | 1670249-37-2.mol |  |
| | Azido-PEG9-acid Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow |
| | Azido-PEG9-acid Usage And Synthesis |
| Description | Azido-PEG9-acid is a PEG molecule consisting of an azide and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU). | | Uses | Azido-PEG9-acid is a non-cleavable 9 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azido-PEG9-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Azido-PEG9-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs; Non-cleavable Linker | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG9-acid Preparation Products And Raw materials |
|