m-PEG5-phosphonic acid

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m-PEG5-phosphonic acid Basic information
Product Name:m-PEG5-phosphonic acid
Synonyms:m-PEG5-phosphonic acid;Phosphonic acid, P-3,6,9,12,15-pentaoxahexadec-1-yl-
CAS:1807512-39-5
MF:C11H25O8P
MW:316.29
EINECS:
Product Categories:
Mol File:1807512-39-5.mol
m-PEG5-phosphonic acid Structure
m-PEG5-phosphonic acid Chemical Properties
Boiling point 453.0±55.0 °C(Predicted)
density 1.211±0.06 g/cm3(Predicted)
pka2.14±0.10(Predicted)
Safety Information
MSDS Information
m-PEG5-phosphonic acid Usage And Synthesis
Descriptionm-PEG5-phosphonic acid ethyl ester is a PEG chain linker. The hydrophilic PEG linkers increase the water solubility of compound in aqueous media. Longer PEG chains have better water solubility properties relative to shorter PEG chains.
Usesm-PEG5-phosphonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
m-PEG5-phosphonic acid Preparation Products And Raw materials
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