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| | 5-Methoxypyridazin-3(2H)-one Basic information |
| Product Name: | 5-Methoxypyridazin-3(2H)-one | | Synonyms: | 5-methoxypyridazin-3-ol;AURORA KA-3645;5-Methoxy-2,3-dihydropyridazin-3-one;3-hydroxy-5-Methoxypyridazine;-METHOXYPYRIDAZIN-3(2H)-ONE;3-methoxy-3(2H)-pyridazinone;3(2H)-Pyridazinone,5-methoxy-;5-methoxypyridazin-3-ol 3-hydroxy-5-Methoxypyridazine | | CAS: | 123696-01-5 | | MF: | C5H6N2O2 | | MW: | 126.11 | | EINECS: | 200-001-2 | | Product Categories: | | | Mol File: | 123696-01-5.mol |  |
| | 5-Methoxypyridazin-3(2H)-one Chemical Properties |
| Melting point | 148-150 °C | | density | 1.30±0.1 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 10.57±0.40(Predicted) | | Appearance | White to off-white Solid | | InChI | InChI=1S/C5H6N2O2/c1-9-4-2-5(8)7-6-3-4/h2-3H,1H3,(H,7,8) | | InChIKey | NRILSJUKEHQBLU-UHFFFAOYSA-N | | SMILES | C1(=O)NN=CC(OC)=C1 |
| | 5-Methoxypyridazin-3(2H)-one Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 5-methoxypyridazin-3(2H)-one from the compound (CAS: 938045-16-0): a mixture of 10% palladium/carbon (100 mg), 2-((benzyloxy)methyl)-4-chloro-5-methoxypyridazin-3(2H)-one (1.34 g), and acetic acid (10 mL) was subjected to a hydrogen atmosphere (0.8 MPa) with the addition of methanol (30 mL) and the reaction was stirred at 50 °C for 10 hours. After completion of the reaction, the insoluble material was removed by filtration and the solvent was removed by distillation under reduced pressure to afford the target product 5-methoxypyridazin-3(2H)-one (611 mg). Mass spectrometry analysis showed m/z (M + H): 127. | | References | [1] Patent: US2015/322063, 2015, A1. Location in patent: Paragraph 2479; 2480; 2481 |
| | 5-Methoxypyridazin-3(2H)-one Preparation Products And Raw materials |
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