N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY

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Company Name: Shenzhen Nexconn Pharmatechs Ltd
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Products Intro: Product Name:N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly
CAS:83960-27-4
Purity:98% Package:1KG;10KG;50KG
Company Name: Nextpeptide Inc
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Products Intro: Product Name:N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly
CAS:83960-27-4
Purity:98% Min. Package:5KG;1KG
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Products Intro: Product Name:Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH
CAS:83960-27-4
Purity:0.95 Package:1mg;5mg;10mg;50mg;100mg,1g
Company Name: Changsha MOL Changes Biotechnology Co., Ltd.
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Products Intro: Product Name:N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly
CAS:83960-27-4
Purity:99% Package:5mg;10mg;100mg;1g;10g;100g
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
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Products Intro: Product Name:Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH
CAS:83960-27-4
Remarks:332P460
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Basic information
Product Name:N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY
Synonyms:Dansyl-D-Ala-Gly-4-nitro-Phe-Gly-OH trifluoroacetate salt;Dansyl-D-Ala-Gly-4-nitro-Phe-Glu-OH;N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY;N-DANSYL-D-ALA-GLY-P-NITRO-PHE-GLY;2-((S)-2-(2-((R)-2-(5-(diMethylaMino)naphthalene-1-sulfonaMido)propanaMido)acetaMido)-3-(4-nitrophenyl)propanaMido)acetic acid;DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY-OH TRIFLUOROACETATE;Glycine, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-D-alanylglycyl-4-nitro-L-phenylalanyl-;N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly
CAS:83960-27-4
MF:C28H32N6O9S
MW:628.65
EINECS:
Product Categories:EnkephalinaseEnzyme Substrates;Enkephalinase;Enzyme Substrates;Protease Substrates;Substrates by Enzyme
Mol File:83960-27-4.mol
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Structure
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Chemical Properties
storage temp. −20°C
solubility methanol: 50mg
form powder
Sequence{Dansyl}-{d-Ala}-Gly-{Phe(pNO2)}-Gly
InChIKeyMIHGGGACSSHXPY-UHFFFAOYSA-N
SMILESCC(NS(=O)(=O)c1cccc2c(cccc12)N(C)C)C(=O)NCC(=O)NC(Cc3ccc(cc3)N(=O)=O)C(=O)NCC(O)=O
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
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SigmaAldrich English
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Usage And Synthesis
UsesDansyl-D-Ala-Gly-Phe(pNO2)-Gly is a synthetic peptide substrate. As a substrate of NEP, Dansyl-D-Ala-Gly-Phe(pNO2)-Gly can be specifically recognized and cleaved by the enzyme, thereby releasing the fluorophore dansyl, which can be quantitatively detected. Therefore, it is often used to determine the activity of NEP[1].
References[1] Niikura T, et al. A humanin derivative reduces amyloid beta accumulation and ameliorates memory deficit in triple transgenic mice[J]. PloS one, 2011, 6(1): e16259. DOI:10.1371/journal.pone.0016259
N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY Preparation Products And Raw materials
Tag:N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY(83960-27-4) Related Product Information
N-(2-Hydroxyethyl)-3-(4-nitrophenyl)propylamine N-ACETYL-2-(4-NITROPHENYL)ETHYLAMINE Benzenepropanamine, 4-amino- (9CI) Dansyl ethylenediamine 3-(4-NITROPHENYL)PROPAN-1-AMINE N-DANSYL-D-ALA-GLY-4-NITRO-PHE-GLY