DANSYL ethylenediamine manufacturers
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| | DANSYL ethylenediamine Basic information |
| | DANSYL ethylenediamine Chemical Properties |
| Melting point | 145-146°C | | Boiling point | 470.2±55.0 °C(Predicted) | | density | 1.262±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | methanol: soluble1mg/mL, clear, slightly yellow to deep yellow | | pka | 11.30±0.50(Predicted) | | form | Solid | | color | Light Yellow | | BRN | 2817535 |
| Hazard Codes | Xn | | Risk Statements | 22-36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | HS Code | 38220090 |
| | DANSYL ethylenediamine Usage And Synthesis |
| Description | Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: λex=335nm, λem=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner. | | Chemical Properties | Yellow to orange powder. | | Uses | A fluorescent reagent. | | References | [1] YUKI INOUE. Fluorescent molecularly imprinted polymer thin films for specific protein detection prepared with dansyl ethylenediamine-conjugated O-acryloyl l-hydroxyproline[J]. Biosensors and Bioelectronics, 2013. DOI:10.1016/j.bios.2013.03.005.
[2] ADACHIH. Importance of Glu-125 in the catalytic activity of human renal dipeptidase.[J]. Biochimica et biophysica acta, 1993. DOI:10.1016/0167-4838(93)90276-w.
[3] MALLAMPATI S, AERSCHOT A V, HOOGMARTENS J, et al. Analysis of dideoxyadenosine triphosphate by CE with fluorescence detection. I. Derivatization through the phosphate group[J]. ELECTROPHORESIS, 2007, 28. DOI:10.1002/elps.200700234.
[4] DUDLEY R W, SLOTTERBECK B D, MCINERNEY M F, et al. Fatty acylation enhances cellular localization of dansylated phenylalanines[J]. Molecular and Cellular Biochemistry, 2010, 346: 81-87. DOI:10.1007/s11010-010-0593-4. |
| | DANSYL ethylenediamine Preparation Products And Raw materials |
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