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Propargyl-PEG5-CH2CO2-NHS manufacturers
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| | Propargyl-PEG5-CH2CO2-NHS Basic information |
| Product Name: | Propargyl-PEG5-CH2CO2-NHS | | Synonyms: | Propargyl-PEG5-CH2CO2-NHS;Propargyl-PEG4-O-C1-NHS ester;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;Propargyl-PEG4-CH2COONHS;Propargyl-PEG5-CH2COO-NHS ester;Propargyl-PEG5-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 3,6,9,12,15-pentaoxaoctadec-17-ynoate;Propargyl-PEG4-CH2CONHS ester | | CAS: | 1161883-51-7 | | MF: | C17H25NO9 | | MW: | 387.38 | | EINECS: | | | Product Categories: | | | Mol File: | 1161883-51-7.mol |  |
| | Propargyl-PEG5-CH2CO2-NHS Chemical Properties |
| storage temp. | Storage temp. -20°C | | solubility | Soluble in DMSO, DCM, DMF | | form | Viscous Liquid | | color | Colorless to light brown |
| | Propargyl-PEG5-CH2CO2-NHS Usage And Synthesis |
| Description | Propargyl-PEG5-CH2CO2-NHS is an amine reactive linker with an alkyne moeity which can react with azide-bearing biomolecules in copper catalyzed Click Chemistry reactions. The PEG units enhance the solubility of the linker in aqueous media. | | Uses | Propargyl-PEG4-O-C1-NHS ester (compound 8) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG4-O-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Kussrow A, et al. Measurement of monovalent and polyvalent carbohydrate-lectin binding by back-scatteringinterferometry. Anal Chem. 2009 Jun 15;81(12):4889-97. DOI:10.1021/ac900569c |
| | Propargyl-PEG5-CH2CO2-NHS Preparation Products And Raw materials |
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