Propargyl-PEG5-CH2CO2tBu manufacturers
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| | Propargyl-PEG5-CH2CO2tBu Basic information |
| Product Name: | Propargyl-PEG5-CH2CO2tBu | | Synonyms: | Propargyl-PEG5-CH2CO2tBu;Propargyl-PEG4-O-C1-Boc;3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester;Propargyl-PEG5-CH2COOtBu;Propargyl-PEG5-CH2COOH t-Bu Ester;Propargyl-PEG4-CH2COOtBu/3,6,9,12,15-Pentaoxaoctadec-17-ynoic acid, 1,1-dimethylethyl ester;tert-butyl 2-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]acetate;Propargyl-PEG5-CH2CO2 t-Bu Ester | | CAS: | 2098489-63-3 | | MF: | C17H30O7 | | MW: | 346.42 | | EINECS: | | | Product Categories: | | | Mol File: | 2098489-63-3.mol |  |
| | Propargyl-PEG5-CH2CO2tBu Chemical Properties |
| Boiling point | 406.8±40.0 °C(Predicted) | | density | 1.055±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | color | Light yellow to yellow |
| | Propargyl-PEG5-CH2CO2tBu Usage And Synthesis |
| Description | Propargyl-PEG5-CH2CO2tBu enables the formation of triazole linkages with azide compounds or biomolecules in copper catalyzed Click Chemistry reactions. The t-butyl group can be hydrolyzed under acidic conditions. | | Uses | Propargyl-PEG4-O-C1-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-O-C1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs; Alkyl/ether | | References | [1] Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461. DOI:10.1021/acs.jmedchem.6b01781 |
| | Propargyl-PEG5-CH2CO2tBu Preparation Products And Raw materials |
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