- Tetramethylguanidine
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- $999.00
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2026-07-27
- CAS:80-70-6
- Min. Order: 1ton
- Purity: 99%
- Supply Ability: 5000
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| | Tetramethylguanidine Basic information |
| Product Name: | Tetramethylguanidine | | Synonyms: | 1,1,3,3-Tetramethyl Guanidine (TMG);1,1,3,3-Tetramethylgyanidine, 97+%;1,1,3,3-Tetramethylguanidine,99%;N,N,N,N-Tetramethy1 Guanidine;1,1,3 tetramethyl guanidine;1,1,3,3-Tertamethylguanidine=TMG;Guanidine, 1,1,3,3-tetramethyl-;Guanidine, N,N,N',N'-tetramethyl- | | CAS: | 80-70-6 | | MF: | C5H13N3 | | MW: | 115.18 | | EINECS: | 201-302-7 | | Product Categories: | Various hydrocyanic acid derivatives;Glycosylating Reagents;Bioactive Small Molecules;Building Blocks;Carbohydrate Chemistry;Cell Biology;Chemical Biology;Chemical Synthesis;Guanidines;Nitrogen Compounds;Organic Building Blocks;T;Hydrocyanic acid derivatives;Antidote / Antibiotic / Antimicrobial;80-70-6 | | Mol File: | 80-70-6.mol |  |
| | Tetramethylguanidine Chemical Properties |
| Melting point | -30 °C | | Boiling point | 162-163 °C (lit.) | | density | 0.916 g/mL at 20 °C (lit.) | | vapor pressure | 0.2 mm Hg ( 20 °C) | | refractive index | n20/D 1.469 | | Fp | 140 °F | | storage temp. | Store below +30°C. | | solubility | Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly) | | pka | 15.20±0.70(Predicted) | | form | Liquid | | color | APHA: ≤150 | | PH | 12.7 (10g/l, H2O, 25℃) | | Relative polarity | 5.5 | | Odor | mild ammoniacal odor | | explosive limit | 1.0-7.5%(V) | | Water Solubility | miscible | | Sensitive | Air Sensitive | | BRN | 969608 | | Dielectric constant | 23.100000000000001 | | Stability: | Stable. Combustible. Incompatible with strong oxidizing agents, mineral and organic acids, carbon dioxide. Air-sensitive. | | InChI | 1S/C5H13N3/c1-7(2)5(6)8(3)4/h6H,1-4H3 | | InChIKey | KYVBNYUBXIEUFW-UHFFFAOYSA-N | | SMILES | CN(C)C(=N)N(C)C | | LogP | -0.49 at 20℃ | | CAS DataBase Reference | 80-70-6(CAS DataBase Reference) | | NIST Chemistry Reference | N,N,N',N'-Tetramethylguanidine(80-70-6) | | EPA Substance Registry System | Guanidine, N,N,N',N'-tetramethyl- (80-70-6) |
| Hazard Codes | C | | Risk Statements | 22-34-20/22-10 | | Safety Statements | 26-27-36/37/39-45-16 | | RIDADR | UN 2920 8/PG 2 | | WGK Germany | 1 | | F | 9-23 | | Autoignition Temperature | 222 °C | | Hazard Note | Harmful/Corrosive | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29252000 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Met. Corr. 1
Skin Corr. 1B | | Toxicity | LD50 orally in Rabbit: 835 mg/kg |
| | Tetramethylguanidine Usage And Synthesis |
| Chemical Properties | N,N,N',N' -Tetramethylguanidine (TMG) [80-70-6], C5H13N3, Mr 115.18, is a stable, unusually strong base, pKa 13.6 (25 ℃), with a free imino group. It is a colorless to light-yellow liquid, miscible with water and common organic solvents: 0.92 g/cm3 (25 ℃), bp 160 ℃, vapor pressure 0.03 kPa (25℃). | | Uses | Tetramethylguanidine (TMG) is used as polyurethane foam catalyst, as accelerator for the syntheses of polysulfured rubber, as a strong base in the photochemical (e.g. couplers) and in the pharmaceutical (e.g. steroids) industries. Product Data Sheet | | Uses | Base employed in the preparation of alkyl nitriles from alkyl halides and 3′-alkylthymidines from 3′-nitrothymidines. | | Uses | 1,1,3,3-Tetaramethylguanidine is used as a strong, non-nucleophilic base for alkylations in organic synthesis. 1,1,3,3-Tetramethylguanidine is an efficient and selective catalyst for the benzoylation
of alcohols. | | Flammability and Explosibility | Flammable | | Synthesis | Prepared from cyanogen chloride and dimethylamine in a 1 : 2 molar
ratio, TMG is used as a polyurethane foam
catalyst, in the preparation of pigments for color
photography, and in steroid synthesis. | | Purification Methods | Reflux it over granulated BaO, then fractionally distil it. Protect it from CO2. [Beilstein 4 IV 227.] |
| | Tetramethylguanidine Preparation Products And Raw materials |
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