| Company Name: |
Biolab Reagents |
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027-65279366 18108604356 |
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products@biolabreagent.com |
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ACROBiosystems |
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13121935750 |
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jiaxin.zhao@acrobiosystems.com |
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| | CARDIOTROPHIN-1, HUMAN Basic information |
| Product Name: | CARDIOTROPHIN-1, HUMAN | | Synonyms: | HUMAN CARDIOTROPHIN-1;HUMAN CT-1;CARDIOTROPHIN-1;CARDIOTROPHIN-1, HUMAN;CARDIOTROPHIN-1, HUMAN, RECOMBINANT;CARDIOTROPHIN-1, HUMAN, RECOMBINANT, E COLI;RHCT-1;RECOMBINANT HUMAN CARDIOTROPHIN-1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | Elisa Kit-Rat Elisa Kit | | Mol File: | Mol File | ![CARDIOTROPHIN-1, HUMAN Structure]() |
| | CARDIOTROPHIN-1, HUMAN Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | biological source | human |
| WGK Germany | WGK 3 | | Storage Class | 13 - Non Combustible Solids |
| | CARDIOTROPHIN-1, HUMAN Usage And Synthesis |
| Uses | Cardiotrophin-1 belongs to the interleukin-6 (IL-6) family of cytokines. It is a cytoprotective protein. The gene is mapped to human chromosome 16p11.
Recombinant human Cardiotrophin-1 is a 22.5kDa protein containing 200 amino acid residues. | | Biological Activity | Cardiotrophin-1 signals via β receptor glycoprotein 130 (gp130) and β receptor leukemia inhibitory factor receptor (LIFR). It confers protective role on cardiac myocytes. Cardiotrophin-1 protects cardiomyocytes from cell death, however, it can also induce cardiac hypertrophy. It is also involved in neural tissue development and helps in protection of the mature nervous system from injuries and dysfunction. Cardiotrophin-1 also protects liver against injury. It is also involved in the control of body weight and intermediate metabolism. In mouse model, it protects β cells from apoptosis. It also promotes glucose-mediated insulin secretion. Absence of the cardiotrophin-1 gene in mice is associated with obesity, hyperglycemia, hyperinsulinemia and hypercholesterolemia. |
| | CARDIOTROPHIN-1, HUMAN Preparation Products And Raw materials |
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