Ac-IETD-CHO

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Ac-IETD-CHO Suppliers list
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 18930552037
Email: 3bsc@sina.com
Company Name: Beijing Ouhe Technology Co., Ltd  
Tel: 13552068683 13522913783
Email: 2355560935@qq.com
Company Name: VDM Biochemicals   
Tel: 0330-2528181
Email: sales@vdmbio.com
Company Name: Shanghai Hanhong Scientific Co.,Ltd.  
Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Company Name: Chemsky (shanghai) International Co.,Ltd  
Tel: 021-50135380
Email: shchemsky@sina.com

Ac-IETD-CHO manufacturers

  • Ac-?IETD-?CHO
  • Ac-?IETD-?CHO pictures
  • $1980.00
  • 2026-07-15
  • CAS:191338-86-0
  • Purity:
  • Supply Ability: 10g
Ac-IETD-CHO Basic information
Product Name:Ac-IETD-CHO
Synonyms:GRANZYME B INHIBITOR II, CELL-PERMEABLE;AC-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-ILE-GLU-THR-ASP-CHO;ACETYL-L-ISOLEUCYL-L-GLUTAMYL-L-THREONYL-L-ASPART-1-AL;N-ACETYL-ILE-GLU-THR-ASP-CHO (ALDEHYDE);Acetyl-isoleucyl-glutamyl-threonyl-aspartal;N-Acetyl-Ile-Glu-Thr-Asp-al ;AC-ILE-GLU-THR-ASP-ALDEHYDE;AC-ILE-GLU-THR-ASP-ALDEHYDE (PSEUDO ACID)
CAS:191338-86-0
MF:C21H34N4O10
MW:502.52
EINECS:
Product Categories:Pepetides;peptides;Caspases/Apoptosis
Mol File:191338-86-0.mol
Ac-IETD-CHO Structure
Ac-IETD-CHO Chemical Properties
Boiling point 971.868±65.00 °C(Press: 760.00 Torr)(predicted)
density 1.304±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. −20°C
solubility H2O: 1 mg/mL
pka4.190±0.10(predicted)
form powder
color white
SequenceAc-Ile-Glu-Thr-Asp-CHO
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
Ac-IETD-CHO Usage And Synthesis
UsesAc- IETD- CHO is a potent, reversible inhibitor of granzyme B and caspase-8. Ac- IETD- CHO inhibits Fas-mediated apoptotic cell death, hemorrhage, and liver failure. Ac- IETD- CHO also inhibits cytotoxic T lymphocytes induced cell death[1][2].
Biological ActivityCell permeable: yes', 'Primary Target
caspase-8', 'Product does not compete with ATP.', 'Reversible: yes
References[1] Bajt ML, et al. Protection against Fas receptor-mediated apoptosis in hepatocytes and nonparenchymal cells by a caspase-8 inhibitor in vivo: evidence for a postmitochondrial processing of caspase-8. Toxicol Sci. 2000 Nov;58(1):109-17. DOI:10.1093/toxsci/58.1.109
[2] Hayashida M, et al. Cell death induction by CTL: perforin/granzyme B system dominantly acts for cell death induction in human hepatocellular carcinoma cells. Proc Soc Exp Biol Med. 2000 Nov;225(2):143-50. DOI:10.1046/j.1525-1373.2000.22518.x
Ac-IETD-CHO Preparation Products And Raw materials
Tag:Ac-IETD-CHO(191338-86-0) Related Product Information
Ac-VEID-AMC Ac-LEHD-CHO Ac-VDVAD-CHO Ac-DEVD-CHO Ac-LEVD-CHO Ac-Ile-Glu-Thr-Asp-CHO TFA Ac-IETD-PNA Caspase 3 (163-175) Ac-IETD-AFC Ac-IETD-CHO GRANZYME B