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| | cis-2-Aminocyclohexanol hydrochloride Basic information | | Application |
| Product Name: | cis-2-Aminocyclohexanol hydrochloride | | Synonyms: | AminocyclohexanolHCl,cis-2-;cis-2-Aminocyclohexanol hydrochloride, 99+%;cis-2-Aminocyclohexanol hydrochloride(racemic);Cyclohexanol, 2-aMino-, hydrochloride, cis-;cis-2-AMinocyclohexanol hydrochloride, 99+% 1GR;(1R,2S)-rel-2-AMinocyclohexanol hydrochloride;cis-2-Aminocyclohexanol hydrochloride, 98.5%;Cyclohexanol, 2-amino-, hydrochloride (1:1), (1R,2S)-rel- | | CAS: | 6936-47-6 | | MF: | C6H13NO.ClH | | MW: | 151.63 | | EINECS: | | | Product Categories: | | | Mol File: | 6936-47-6.mol |  |
| | cis-2-Aminocyclohexanol hydrochloride Chemical Properties |
| Melting point | 186-190 °C | | storage temp. | Inert atmosphere,Room Temperature | | form | Crystalline Powder | | color | White to slightly beige | | CAS DataBase Reference | 6936-47-6 |
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ACROS
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| | cis-2-Aminocyclohexanol hydrochloride Usage And Synthesis |
| Application | cis-2-aminocyclohexanol hydrochloride can be used as a pharmaceutical synthesis intermediate. | | Chemical Properties | white to slightly beige crystalline powder | | Synthesis | Cis-2-aminocyclohexanol hydrochloride was prepared as follows:
1) To a mixture of cooled m-chloroperbenzoic acid (9.87 g; 57.19 mmol) in 125 ml of CH2Cl2 was slowly added cyclohexene (5.00 g; 51.99 mmol). The reaction mixture was allowed to warm gradually to room temperature overnight. The mixture was filtered, washed with concentrated NaHCO3 and concentrated in vacuum to give a light yellow oily cyclohexene oxide which was used directly in the next step.
2) In a sealed tube, cyclohexene oxide (5.44 g; 48.50 mmol) and ammonium hydroxide solution (10 ml) in 4 ml of methanol were heated to 80°C for 72 hours. After removing the heat, the mixture was concentrated in vacuum to obtain cis-2-aminocyclohexanol hydrochloride.
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| | cis-2-Aminocyclohexanol hydrochloride Preparation Products And Raw materials |
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