3-O-demethylfortimicin A

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3-O-demethylfortimicin A Basic information
Product Name:3-O-demethylfortimicin A
Synonyms:3-O-demethylfortimicin A;A 49759;A49759;A-49759
CAS:74842-47-0
MF:C16H33N5O6
MW:391.466
EINECS:
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Mol File:74842-47-0.mol
3-O-demethylfortimicin A Structure
3-O-demethylfortimicin A Chemical Properties
Safety Information
MSDS Information
3-O-demethylfortimicin A Usage And Synthesis
Uses3-O-Demethylfortimicin A (A-49759) is an aminocyclitol antibiotic with antibacterial activity. 3-O-Demethylfortimicin A is particularly effective against Gram-negative pathogens and staphylococcus[1][2][3].
References[1] Sennello LT, et al. Single-dose pharmacokinetics of 3-O-demethylfortimicin A in humans after intravenous and intramuscular administration. Antimicrob Agents Chemother. 1986 Mar;29(3):400-4. DOI:10.1128/AAC.29.3.400
[2] Girolami RL, et al. Comparative antimicrobial activity of O-demethylfortimicin A, a derivative of fortimicin A. Antimicrob Agents Chemother. 1980 Nov;18(5):766-72. DOI:10.1128/AAC.18.5.766
[3] Yang CL, et al. Comparative vestibular toxicity study with 3-O-demethylfortimicin A disulfate and gentamicin sulfate in cats. Drug Chem Toxicol. 1987;10(3-4):237-56. DOI:10.3109/01480548709042985
3-O-demethylfortimicin A Preparation Products And Raw materials
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cis-1,4-Cyclohexanediamine 1,4-Cyclohexanediamine cis-2-Aminocyclohexanol hydrochloride FORTIMICIN N,N-Dimethylcyclohexane-1,4-diamine 3-O-demethylfortimicin A