- Dimethyl isosorbide
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- $800.00
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2026-08-12
- CAS:5306-85-4
- Min. Order: 25Kg/Drum
- Purity: 99
- Supply Ability: 1000T
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| | Isosorbide dimethyl ether Basic information |
| Product Name: | Isosorbide dimethyl ether | | Synonyms: | ISOSORBIDE DIMETHYL ETHER;2,5-DI-O-METHYL-1,4:3,6-DIANHYDRO-D-GLUCITOL;1,4:3,6-DIANHYDRO-2,5-O-DIMETHYL-D-GLUCITOL;1,4:3,6-DIANHYDROSORBITOL 2,5-DIMETHYL ETHER;-3,6-Dimethoxyhexahydrofuro[3,2-b]furan;Isosorbide dimethyl ether (Dimethyl Isosorbide);Dimethyl isosorbide 99% (DMI);2,5-dimethylisosorbide | | CAS: | 5306-85-4 | | MF: | C8H14O4 | | MW: | 174.2 | | EINECS: | 226-159-8 | | Product Categories: | Cosmetic;5306-85-4;1 | | Mol File: | 5306-85-4.mol |  |
| | Isosorbide dimethyl ether Chemical Properties |
| Melting point | -70°C | | Boiling point | 93-95 °C0.1 mm Hg(lit.) | | density | 1.15 g/mL at 25 °C(lit.) | | vapor pressure | 12.54Pa at 20℃ | | refractive index | n20/D 1.461(lit.) | | Fp | 227 °F | | storage temp. | Sealed in dry,Room Temperature | | form | Liquid | | color | Clear colorless to light yellow | | PH | 7.0-8.0 (100g/l, H2O, 20℃) | | Optical Rotation | [α]21/D +96.1°, c = 2 in chloroform | | Water Solubility | Soluble in water. | | BRN | 80854 | | Cosmetics Ingredients Functions | SOLVENT
VISCOSITY CONTROLLING | | InChI | 1S/C8H14O4/c1-9-5-3-11-8-6(10-2)4-12-7(5)8/h5-8H,3-4H2,1-2H3/t5-,6+,7-,8-/m1/s1 | | InChIKey | MEJYDZQQVZJMPP-ULAWRXDQSA-N | | SMILES | CO[C@H]1COC2[C@@H](COC12)OC | | LogP | -1.62 | | CAS DataBase Reference | 5306-85-4(CAS DataBase Reference) |
| Safety Statements | 23-24/25 | | WGK Germany | 3 | | TSCA | TSCA listed | | HS Code | 29092000 | | Storage Class | 10 - Combustible liquids |
| | Isosorbide dimethyl ether Usage And Synthesis |
| Chemical Properties | clear colorless to light yellow liquid. very stable under neutral conditions, hygroscopic and miscible with most organic solvents. | | Uses | dimethyl isosorbide is a carrier, solvent, and viscosity controller. Its particular skin-penetrating ability opens the possibility of enhancing active substance efficacy in optical products. Its physical characteristics and solubility properties are superior to those of propylene glycol, glycerin, or ethyl alcohol. | | Uses | Isosorbide dimethyl ether (DMI), a sustainable solvent, is widely used in various cosmetic and pharmaceutical formulations.
General applications:
DMI can be used as an alternative green solvent for epoxidation of cyclooctene, Baylis–Hillman reaction of isomaltulose-derived aldehydes with α,β-unsaturated ketones and also in solid-phase synthesis.
It can be used as a coalescent for water-borne paints, where it acts as a co-solvent during the water loss phase and as a coalescing agent during the film formation. | | Preparation | Isosorbide dimethyl ether is synthesized from isosorbide by methylation.
Isosorbide dimethyl ether is obtained from stock like D-sorbitol, which is mainly derived from the hydrogenation of D-glucose.
Isosorbide dimethyl has a low level of toxicity and is referred to as a green solvent due to its production from renewable/raw material.
The boiling point of this solvent is high.
lt is used as a substitute to dimethyl sulfoxide,and dimethylformamide-like solvents. | | General Description | Dimethyl isosorbide (DMI) is a biobased greener solvent and thus aligns with "Use of Renewable Feedstocks" and "Safer Solvents and Auxiliaries". | | Flammability and Explosibility | Non flammable | | Synthesis | The general procedure for the synthesis of (3S,3aR,6R,6aR)-6-methoxyhexahydrofuro[3,2-b]furan-3-ol, (3R,3aR,6S,6aR)-6-methoxyhexahydrofuro[3,2-b]furan-3-ol, and isosorbide dimethylether using ethylene glycol dimethyl ether and isosorbide as raw materials is as follows: isosorbide, 1,2-dimethoxyethane ( ethylene glycol dimethyl ether) and heteropolyacid were sequentially added into a stainless steel high-pressure reactor and the reactor was sealed. The reaction mixture was magnetically stirred at 150°C for 5 hours. The molar ratio of 1,2-dimethoxyethane to isosorbide was 20:1, and the mass ratio of heteropolyacid to isosorbide was 0.2:1. After the reaction was completed, the reactor was cooled to room temperature. The reaction mixture was analyzed using gas chromatography, and the conversion and yield of the methylated product of isosorbide was calculated as molar percentage (mol%) by internal standard method. | | References | [1] Patent: CN105646514, 2016, A. Location in patent: Paragraph 0041; 0042; 0043; 0044; 0045; 0046
[2] RSC Advances, 2015, vol. 5, # 31, p. 24139 - 24143 |
| | Isosorbide dimethyl ether Preparation Products And Raw materials |
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