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ChemShuttle, Inc. |
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0510-83588313-811 18800520310 |
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VH032-C4-NH2 dihydrochloride manufacturers
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| | VH032-C4-NH2 dihydrochloride Basic information |
| Product Name: | VH032-C4-NH2 dihydrochloride | | Synonyms: | VH032-C4-NH2 dihydrochloride;(S,R,S)-AHPC-C4-NH2 dihydrochloride;VH 032 amide-alkylC4-amine;(2S,4R)-1-((S)-2-(5-aminopentanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride;(S,R,S)-AHPC-C4-NH2 2HCl | | CAS: | 2341796-78-7 | | MF: | C27H40ClN5O4S | | MW: | 566.16 | | EINECS: | | | Product Categories: | | | Mol File: | 2341796-78-7.mol |  |
| | VH032-C4-NH2 dihydrochloride Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | Light yellow to green yellow |
| | VH032-C4-NH2 dihydrochloride Usage And Synthesis |
| Uses | (S,R,S)-AHPC-C4-NH2 dihydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1]. | | IC 50 | VHL | | storage | Store at -20°C | | References | [1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004 |
| | VH032-C4-NH2 dihydrochloride Preparation Products And Raw materials |
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