| Company Name: |
ChemShuttle, Inc. |
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0510-83588313-811 18800520310 |
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sales@chemshuttle.com |
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| | VH 032-linker 7 Basic information |
| Product Name: | VH 032-linker 7 | | Synonyms: | VH 032-linker 7;VH 032 amide-alkylC2-amine;(S,R,S)-AHPC-C2-NH2 dihydrochloride;(2S,4R)-1-((S)-2-(3-aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride;(2S,4R)-1-((S)-2-(3-Aminopropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide dihydrochloride;VH 032 amide-alkylC2-amine dihydrochloride;(S,R,S)-AHPC-C2-NH2 2HCl | | CAS: | 2341796-73-2 | | MF: | C25H36ClN5O4S | | MW: | 538.1 | | EINECS: | | | Product Categories: | | | Mol File: | 2341796-73-2.mol |  |
| | VH 032-linker 7 Chemical Properties |
| solubility | Soluble in DMSO | | form | Solid | | color | White to yellow |
| | VH 032-linker 7 Usage And Synthesis |
| Uses | (S,R,S)-AHPC-C2-NH2 dihydrochloride incorporates a VHL ligand for the E3 ubiquitin ligase, and a PROTAC linker. (S,R,S)-AHPC-OH can be used in the synthesis of a series of PROTACs[1]. | | IC 50 | VHL | | storage | Store at -20°C | | References | [1] Jing Liu, et al. Tropomyosin receptor kinase (trk) degradation compounds and methods of use. WO2020038415A1. |
| | VH 032-linker 7 Preparation Products And Raw materials |
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