2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate

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2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate Basic information
Product Name:2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate
Synonyms:2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate;SPDMB;Butanoic acid, 3-methyl-3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)buta
CAS:2101206-29-3
MF:C14H16N2O4S2
MW:340.42
EINECS:
Product Categories:
Mol File:2101206-29-3.mol
2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate Structure
2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate Chemical Properties
Boiling point 472.9±55.0 °C(Predicted)
density 1.39±0.1 g/cm3(Predicted)
pka1.79±0.19(Predicted)
Safety Information
MSDS Information
2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate Usage And Synthesis
UsesSPDMB is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs)[1].
IC 50Disulfide Cleavable Linker
2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate Preparation Products And Raw materials
Tag:2,5-Dioxopyrrolidin-1-yl 3-methyl-3-(pyridin-2-yldisulfanyl)butanoate(2101206-29-3) Related Product Information
Py-ds-dMBut-OSu SPDP N-succiniMidyl 4-(2-pyridyldithio)pentanoate SPDB Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate N-succinimidyl-3-(2-pyridyldithio)butyrate