腺苷5'-三磷酸二钠盐水合物
| 中文名称 | 腺苷5'-三磷酸二钠盐水合物 |
|---|---|
| 中文同义词 | 腺苷-5′-三磷酸二钠盐，（无钙）;三磷酸腺苷二钠盐/ATP二钠盐;ADENOSINE 5'-TRIPHOSPHATE DISODIUM SALT HYDRATE 三磷酸腺苷二钠;5-腺苷三磷酸二钠盐三水物;5-腺苷三磷酸二钠盐水合物;三磷酸腺苷二钠盐水合物;ATP二钠盐水合物;5'-三磷酸腺苷二钠,磷酸腺苷钠 |
| 英文名称 | ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL& |
| 英文同义词 | Adenosine Impurity 9;-TRIPHOSPHATE DISODIUM SAL&5μ-ATP-Na2, ATP hydrate disodium salt;Adenosine-5'-triphosphate disodium salt hydrate, 99+% (water <10%);Adenosine 5'-triphosphate, disodium salt hydrate,98%;Adenosine-5'-triphosphate disodium salt hydrate, water <10%;Adenosine 5′-triphosphate disodium salt hydrate,5′-ATP-Na2, ATP disodium salt hydrate;Adenosine 5′-triphosphate disodium salt hydrate,ATP disodium salt |
| CAS号 | 34369-07-8 |
| 分子式 | C10H19N5NaO14P3 |
| 分子量 | 549.19 |
| EINECS号 | 213-579-1 |
| 相关类别 | 小分子抑制剂，天然产物;杂环;植物激素及核酸类;医药原料药;生化试剂;腺苷;小分子抑制剂;含硫化合物;核苷，核苷酸，寡核苷酸;生化试剂-植物激素及核酸类;化工原料;中间体-有机中间体;Inhibitors;Pharmaceutical;通用生化试剂-核酸;化学试剂;食品添加剂 |
| Mol文件 | 34369-07-8.mol |
| 结构式 |  |
腺苷5'-三磷酸二钠盐水合物 性质
| 熔点 | 176 °C (dec.)(lit.) |
|---|---|
| 储存条件 | -20°C |
| 溶解度 | 在水中的溶解度为50mg/mL，透明，无色 |
| 酸度系数(pKa) | (1) 4.0, (2) 6.5 |
| 形态 | 粉末 |
| 颜色 | 白色 |
| 生物来源 | microbial (Corynebacterium sp.) |
| 水溶解性 | Soluble in water. |
| 最大波长(λmax) | 259 nm |
| 敏感性 | Light Sensitive & Hygroscopic |
| Merck | 14,155 |
| BRN | 3585462 |
| 稳定性 | 吸湿性、温度敏感 |
| InChIKey | NTBQNWBHIXNPRU-MSQVLRTGSA-L |
| SMILES | [Na+].[Na+].[H]O[H].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O |
| CAS 数据库 | 34369-07-8 |
ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.
ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.
| Animal Model: | Four-week-old Kunming mice (18-22 g) |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection, before bacterial ( E. coli ) challenge |
| Result: | Protected mice from bacterial infection. |
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/07/06 | L14522 | 腺苷-5'-三磷酸二钠盐水合物, 99%, water <10% Adenosine-5'-triphosphate disodium salt hydrate, 99%, water <10% | 34369-07-8 | 1g | 461元 |
| 2026/07/06 | J10585 | 腺苷-5′-三磷酸二钠盐，（无钙） Adenosine-5'-triphosphate disodium salt hydrateThermo Scientific | 34369-07-8 | 100g | 3171元 |