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Garcinolic acid; trans-(SH) manufacturers
- Garcinoic acid
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- $1280.00
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2026-05-11
- CAS:91893-83-3
- Purity:
- Supply Ability: 10g
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| | Garcinolic acid; trans-(SH) Basic information |
| Product Name: | Garcinolic acid; trans-(SH) | | Synonyms: | 2,6,10-Tridecatrienoic acid, 13-[(2R)-3,4-dihydro-6-hydroxy-2,8-dimethyl-2H-1-benzopyran-2-yl]-2,6,10-trimethyl-, (2E,6E,10E)-;Garcinoic acid;Garcinolic acid; trans-(SH) | | CAS: | 91893-83-3 | | MF: | C27H38O4 | | MW: | 426.59 | | EINECS: | | | Product Categories: | | | Mol File: | 91893-83-3.mol |  |
| | Garcinolic acid; trans-(SH) Chemical Properties |
| Boiling point | 602.6±55.0 °C(Predicted) | | density | 1.055±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 30 mg/ml | | form | A film | | pka | 5.00±0.19(Predicted) | | Major Application | metabolomics
vitamins, nutraceuticals, and natural products | | InChIKey | QOFWRHWADNWKSU-LRXIOGKNSA-N | | SMILES | C\C(CC\C=C(/C)C(O)=O)=C/CC\C(C)=C\CC[C@]1(C)CCc2cc(O)cc(C)c2O1 |
| Hazard Codes | T,N | | Risk Statements | 25-50 | | Safety Statements | 61 | | RIDADR | UN 2811 6.1 / PGIII | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 3 Oral
Aquatic Acute 1
Aquatic Chronic 1 |
| | Garcinolic acid; trans-(SH) Usage And Synthesis |
| Description | Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora. It inhibits IL-1β-induced microsomal prostaglandin E2 synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM. It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM. | | Uses | Garcinoic Acid displays anti-angiogenic activity as well as anti-oxidative activity in animals. | | General Description | Natural product derived from plant source. | | References | [1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] KHALED ALSABIL. Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors.[J]. Planta medica, 2016, 82 11-12: 1110-1116. DOI: 10.1055/s-0042-108739
[3] KENJI TERASHIMA Masatake N Yoshiaki Takaya. Powerful antioxidative agents based on garcinoic acid from Garcinia kola[J]. Bioorganic & Medicinal Chemistry, 2002, 10 5: Pages 1619-1625. DOI: 10.1016/s0968-0896(01)00428-x |
| | Garcinolic acid; trans-(SH) Preparation Products And Raw materials |
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