Mal-PEG2-CH2CH2COOtBu manufacturers
- Mal-PEG2-COOtBu
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2025-06-07
- CAS:1374666-31-5
- Min. Order: 1g
- Purity: >98.00%
- Supply Ability: 1g
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| | Mal-PEG2-CH2CH2COOtBu Basic information |
| Product Name: | Mal-PEG2-CH2CH2COOtBu | | Synonyms: | Mal-PEG2-C2-Boc;Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Mal-PEG-2-C2-Boc,PROTAC Linkers,Inhibitor,inhibit,Mal PEG2 C2 Boc,MalPEG2C2Boc;Mal-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Mal-PEG2-PA-TERT | | CAS: | 1374666-31-5 | | MF: | C15H23NO6 | | MW: | 313.35 | | EINECS: | | | Product Categories: | | | Mol File: | 1374666-31-5.mol |  |
| | Mal-PEG2-CH2CH2COOtBu Chemical Properties |
| Boiling point | 428.7±30.0 °C(Predicted) | | density | 1.167±0.06 g/cm3(Predicted) | | storage temp. | Storage temp. 2-8°C | | form | Liquid | | pka | -2.34±0.20(Predicted) | | color | Colorless to light yellow |
| | Mal-PEG2-CH2CH2COOtBu Usage And Synthesis |
| Description | Mal-PEG2-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Mal-PEG2-CH2CH2COOtBu Preparation Products And Raw materials |
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