Mal-PEG8-alcohol manufacturers
- MAL-PEG8-OH
-
-
2026-07-24
- CAS:2353409-63-7
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
- Mal-PEG8-OH
-
-
2025-06-07
- CAS:2353409-63-7
- Min. Order: 500mg
- Purity: >98.00%
- Supply Ability: 500mg
|
| | Mal-PEG8-alcohol Basic information |
| Product Name: | Mal-PEG8-alcohol | | Synonyms: | Mal-PEG8-alcohol;1H-Pyrrole-2,5-dione,1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricos-1-yl)-;1-(23-Hydroxy-3,6,9,12,15,18,21-heptaoxatricosyl)-1H-pyrrole-2,5-dione;1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione | | CAS: | 2353409-63-7 | | MF: | C20H35NO10 | | MW: | 449.49 | | EINECS: | | | Product Categories: | | | Mol File: | 2353409-63-7.mol |  |
| | Mal-PEG8-alcohol Chemical Properties |
| Boiling point | 559.0±50.0 °C(Predicted) | | density | 1.192±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 14.36±0.10(Predicted) |
| | Mal-PEG8-alcohol Usage And Synthesis |
| Description | Mal-PEG8-alcohol is a PEG linker containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. | | Uses | Mal-PEG8-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Mal-PEG8-alcohol Preparation Products And Raw materials |
|