- Di-8-ANEPPS
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- $99.00
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2026-07-16
- CAS:157134-53-7
- Purity: 99.17%
- Supply Ability: 10g
- DI-8-ANEPPS
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-
2025-06-07
- CAS:157134-53-7
- Min. Order: 100mg
- Purity: >99.00%
- Supply Ability: 100mg
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| | Di-8-anepps Basic information |
| Product Name: | Di-8-anepps | | Synonyms: | 4-(2-[6-(DIOCTYLAMINO)-2-NAPHTHALENYL]ETHENYL)-1-(3-SULFOPROPYL)PYRIDINIUM INNER SALT;Jpw 1153;Di-8-ANEPPS *CAS#: 157134-53-7*;Pyridinium, 4-[2-[6-(dioctylamino)-2-naphthalenyl]ethenyl]-1-(3-sulfopropyl)-, inner salt;3-(4-(2-(6-(Dioctylamino)naphthalen-2-yl)vinyl)pyridin-1-ium-1-yl)propane-1-sulfonate;4-amino-1-((2R,3R,4R,5S)-4-azido-5-(hydroxymethyl)-3-(2-(trifluoromethoxy)ethoxy)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one;Di-8-ANEPPS Membrane Potential Probe;Di-8-anepps | | CAS: | 157134-53-7 | | MF: | C36H52N2O3S | | MW: | 592.87 | | EINECS: | | | Product Categories: | Styryl | | Mol File: | 157134-53-7.mol |  |
| | Di-8-anepps Chemical Properties |
| Melting point | >200℃ | | storage temp. | 2-8°C | | solubility | DMSO: soluble | | form | powder | | color | orange to red | | Appearance | Orange solid | | ex/em | 468/633 nm (artificial membrane) | | λmax | 498 nm | | ε(extinction coefficient) | ≥37 at 495-501 nm in methanol | | Major Application | diagnostic assay manufacturing
hematology
histology | | Biological Applications | Measuring membrane potential | | InChIKey | IXFSUSNUALIXLU-UHFFFAOYSA-N | | SMILES | CCCCCCCCN(CCCCCCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | Di-8-anepps Usage And Synthesis |
| Description | Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker. | | Chemical Properties | Appearance: Orange-red solid
ex/em: 468/633 nm (artificial membrane)
Extinction coefficient (ε): 44,000 Lmol1cm1 (methanol) | | Uses | Di-8-ANEPPS is a potentiometric fluorescent dye that can be used to noninvasively measure transmembrane voltage. It is not fluorescent in water, but when bound to the lipid bilayer, becomes strongly fluorescent (ex/em max = ~467/631 nm). The fluorescence intensity of di-8-ANEPPS varies proportionally to changes in transmembrane voltage. This dye is most suitable for measuring larger changes in membrane voltage, such as the onset of induced membrane voltage in nonexcitable cells exposed to external electric fields or action potentials in excitable cells. Since di-8-ANEPPS stains the membrane, it can also be used simply as a cell membrane marker. | | Uses | Di-8-ANEPPS is a fast-responding membrane potential dye. It is more suitable for long-term membrane potential studies than di-4-ANEPPS (sc-214872) because of its better retention in the outer leaflet of plasma membranes. This dye is weakly fluorescent in aqueous media, and becomes strongly fluorescent upon binding to lipophilic environments (such as membranes). Di-8-ANEPPS is less susceptible for cellular internalization due to the sulfonate group it possesses.Dyes and metabolites. | | References | [1] GORAZD PUCIHAR Damijan M Tadej Kotnik. Measuring the induced membrane voltage with Di-8-ANEPPS.[J]. Jove-Journal of Visualized Experiments, 2009, 33. DOI: 10.3791/1659 | | Abs/Em Maxima | 499/708 nm | | Excitation / Emission Maximum | 467 nm/631 nm |
| | Di-8-anepps Preparation Products And Raw materials |
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