|
|
| | 2,2-Dimethylethenylboronic acid Basic information |
| Product Name: | 2,2-Dimethylethenylboronic acid | | Synonyms: | 2,2-DIMETHYLETHENYLBORONIC ACID 97%;RARECHEM AH PB 0256;Boronic acid,B-(2-methyl-1-propen-1-yl)-;B-(2-methyl-1-propen-1-yl)boronic acid;ethenyL;(2-Methyl-1-propen-1-yl)boronicacid;2,2-Dimethylethenylboronic acid（contains varying amounts of Anhydride）;2,2-Dimethylethenylboronic acid - [D3007] | | CAS: | 14559-88-7 | | MF: | C4H9BO2 | | MW: | 99.92 | | EINECS: | | | Product Categories: | Boronic acids | | Mol File: | 14559-88-7.mol |  |
| | 2,2-Dimethylethenylboronic acid Chemical Properties |
| Melting point | 87 °C | | Boiling point | 190.6±23.0 °C(Predicted) | | density | 0.952±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | solid | | pka | 9.82±0.43(Predicted) | | color | White to off-white |
| | 2,2-Dimethylethenylboronic acid Usage And Synthesis |
| Uses | 2,2-Dimethylethenylboronic acid is a useful reagent in the preparation of prostaglandins via 1,4-conjugate addition. | | Synthesis |
(1) the use of dichloromethane, at 10 ~ 60 conditions, the use of 3,3-dimethyl acrylic acid, and bromine reaction 3 ~ 4h, after the end of the reaction using a base to adjust the PH to 9 ~ 10,30 ~ 60 conditions of the reaction for 2 ~ 3h, the reaction is static after the end of the stratification, the organic layer distillation to obtain 2,2-dimethyl vinyl bromide;
(2) using tetrahydrofuran, at a temperature of -76 ~ -40 C, using 2,2-dimethyl vinyl bromide, in the lithium metal and boronization reagent under the action of the reaction 2 ~ 3h, using hydrochloric acid to adjust the PH to 3 ~ 4, using ethyl acetate extraction, concentrated organic layer by non-polar hydrocarbon solvent slurrying and filtration, drying to obtain 2,2-dimethyl vinylboronic acid.
|
| | 2,2-Dimethylethenylboronic acid Preparation Products And Raw materials |
|