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Product Name:N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE CAS:89108-46-3
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N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE manufacturers
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| | N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Basic information |
| | N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Chemical Properties |
| Melting point | 181-182°C | | storage temp. | 2-8°C | | solubility | H2O: Stock solutions of approx. 5 mM are suggested. Stocks should be stable for at least 6 months when stored at 4°Csoluble | | form | powder | | color | yellow tan | | Water Solubility | water: 1mg/mL ethanol: 5mg/mL | | InChI | 1S/C14H18N2O2S.ClH/c15-9-3-4-10-16-19(17,18)14-8-7-12-5-1-2-6-13(12)11-14;/h1-2,5-8,11,16H,3-4,9-10,15H2;1H | | InChIKey | WYFVKUWCEVMLOL-UHFFFAOYSA-N | | CAS DataBase Reference | 89108-46-3(CAS DataBase Reference) |
| WGK Germany | 3 | | HS Code | 2935909099 | | Storage Class | 11 - Combustible Solids |
| | N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | Calmodulin antagonist that binds to calmodulin and inhibits calcium-ion-calmodulin- regulated activities, including phosphodiesterase activation and myosin light chain kinase | | Uses | N-(4-Aminobutyl)-2-naphthalenesulfonamide Hydrochloride is a calmodulin antagonist that binds calmodulin and inhibits calcium ion calmodulin-regulated activities such as phosphodiesterase activation and myosin light chain kinase (1, 2). | | Biological Activity | Cell permeable: yes', 'Primary Target Myosin light chain kinase (Mlck)', 'Product does not compete with ATP.', 'Reversible: yes', 'Target IC50: 300 μM and 260 μM against myosin light chain kinase and Ca2+-calmodulin-dependent phosphodiesterase, respectively. |
| | N-(4-AMINOBUTYL)-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE Preparation Products And Raw materials |
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