- Saikosaponin A
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- $48.00
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2026-07-15
- CAS:20736-09-8
- Purity: 99.57%
- Supply Ability: 10g
- Saikosaponin A
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2024-04-12
- CAS:20736-09-8
- Min. Order: 1kg
- Purity: 98%
- Supply Ability: 2000ton
- Saikosaponin A
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2023-02-24
- CAS:20736-09-8
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| | Saikosaponin a Basic information |
| Product Name: | Saikosaponin a | | Synonyms: | SAIKOSAPONIN A(RG);Thesaikosaponin A;SAIKOSAPONIN A;dihydroxyolean-11-en-3-yl6-deoxy-3-O-β-D-;β-D-fucoside, (3β,4α,16β)-13,28-epoxy-16,23-;[(3β,4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside;[(4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside;SABINYL ACETATE(RG) | | CAS: | 20736-09-8 | | MF: | C42H68O13 | | MW: | 780.98 | | EINECS: | 633-799-5 | | Product Categories: | chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Saponins | | Mol File: | 20736-09-8.mol |  |
| | Saikosaponin a Chemical Properties |
| Melting point | 225~232℃ (dec.) | | Boiling point | 893.7±65.0 °C(Predicted) | | density | 1.163~1.168 g/ml | | refractive index | 1.571~1.574 (20/D) | | storage temp. | Hygroscopic, Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly) | | pka | 12.83±0.70(Predicted) | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic | | Major Application | food and beverages | | InChIKey | KYWSCMDFVARMPN-FMIBPMOUSA-N | | CAS DataBase Reference | 20736-09-8 |
| Safety Statements | 24/25 | | WGK Germany | WGK 3 | | HS Code | 29389090 | | Storage Class | 11 - Combustible Solids |
| | Saikosaponin a Usage And Synthesis |
| Chemical Properties | Pale yellow crystals, easily soluble in water and dilute alcohol, difficult to dissolve in benzene, ether and chloroform, derived from the aerial parts of Bupleurum chinense. | | Uses | Saikosaponin A was shown to exhibit anti-inflammatory activities by suppressing activation of NF-kB signaling pathway. | | Definition | ChEBI: Saikosaponin A is a saikosaponin. | | in vivo | Saikosaponin A (1-10 mg/kg, i.p, 7 d) attenuates the morphological changes in the small intestine induced by 5-FU[2].
Saikosaponin-A (1-10 mg/kg, i.p, 7 d) enhances the decrease of antioxidant enzymes in intestinal tissue caused by 5-FU[2].
| Animal Model: | 5-FU (HY-90006)-induced mucositis in BALB/c mice modle[2] | | Dosage: | 1, 5, 10mg/kg/day, 7 d | | Administration: | injected intraperitoneally (i.p) | | Result: | Reduced villus blunting, crypt cells apoptosis, and inflammatory cell infiltration.
Decreased concentration of GSH, GST, Catalase, and SOD in intestinal tissue.
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| | Saikosaponin a Preparation Products And Raw materials |
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