- BERBERINE CHLORIDE
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- $1.00 / 2ton
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2026-01-21
- CAS:141433-60-5
- Min. Order: 21ton
- Purity: 99.98
- Supply Ability: ton
- BERBERINE CHLORIDE
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- $10.50 / 1KG
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2025-05-26
- CAS:141433-60-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1 ton
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| | BERBERINE CHLORIDE Basic information |
| Product Name: | BERBERINE CHLORIDE | | Synonyms: | Berberine (berberine hydrochloride);Berberine chloride hydrate 97%;9,10-DiMethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-iuM chloride hydrate;Berberine chloride hydrate technical, >=90% (AT);Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-, chloride, hydrate (1:1:);LABOTEST-BB LT00440956;CI 75160;BERBERIN HCL | | CAS: | 141433-60-5 | | MF: | C20H20ClNO5 | | MW: | 389.83 | | EINECS: | 211-195-9 | | Product Categories: | Alkaloids;Biochemistry;Miscellaneous Natural Products;Isoquinoline Alkaloids | | Mol File: | 141433-60-5.mol |  |
| | BERBERINE CHLORIDE Chemical Properties |
| Melting point | 204-206 °C (dec.) | | storage temp. | Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | Colour Index | 75160 | | form | Solid | | color | Pale Yellow to Yellow | | Water Solubility | Soluble in water. | | Sensitive | Light Sensitive | | Merck | 14,1154 | | BRN | 3836585 | | Stability: | Hygroscopic | | InChI | InChI=1S/C20H18NO4.ClH.H2O/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;;/h3-4,7-10H,5-6,11H2,1-2H3;1H;1H2/q+1;;/p-1 | | InChIKey | VKJGBAJNNALVAV-UHFFFAOYSA-M | | SMILES | O(C1=C(C=CC2=CC3C4=CC5OCOC=5C=C4CC[N+]=3C=C12)OC)C.[Cl-].O | | CAS DataBase Reference | 141433-60-5(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 20/21/22 | | WGK Germany | 2 | | RTECS | DR9866400 | | F | 3-10 | | TSCA | Yes | | HS Code | 29399990 | | Storage Class | 11 - Combustible Solids |
| | BERBERINE CHLORIDE Usage And Synthesis |
| Description | Berberine chloride occurs together with Neprotine (q.v.) in Berberis insignis Hook, B.
umbellata Wall and Mahonia nepalensis DC. (Syn. Berberis nepalensis Spreng.).
It is optically inactive and crystallizes from H2O with 5.5 H2O. It yields crystal_x0002_line salts, e.g. the nitrate, m.p. 265-7°C (dec.); sulphate, m.p. 271-3°C (dec.)
and the picrate, m.p. 231°C (dec.). The base also furnishes a methyl ether, m.p.
265°C and on catalytic hydrogenation gives the tetrahydro derivative, m.p.
213-5°C (dec.). The ultraviolet spectrum resembles that of berberine (q.v.).
Oxidation with KMn04 in Me2CO gives hemipinic acid, identified as the
ethylimide, m.p. 90°C. | | Chemical Properties | Berberine hydrochloride is a yellow crystalline powder; odorless. It is soluble in hot water, slightly soluble in water or ethanol, very slightly soluble in trichloromethane and insoluble in ether. | | Uses | Berberine chloride is mainly used to treat gastroenteritis, dysentery and other intestinal infections, conjunctivitis and suppurative otitis media. | | General Description | Berberine chloride is an alkaloid with antibiotic properties. Berberine chloride induces reactive oxygen species (ROS) production and inhibits DNA topoisomerase. It has anti-tumor properties. | | References | Orekhov.,J. Amer. Pharm. Assoc., 30,247, (1941)
Chatterjee., ibid, 33,205,210 (1944) |
| | BERBERINE CHLORIDE Preparation Products And Raw materials |
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