Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]-

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Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- manufacturers

  • GSK-5503A
  • GSK-5503A pictures
  • $1520.00
  • 2026-05-11
  • CAS:1253186-46-7
  • Purity:
  • Supply Ability: 10g
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- Basic information
Product Name:Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]-
Synonyms:Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]-;GSK-5503A;2,6-Difluoro-N-(1-(2-phenoxybenzyl)-1H-pyrazol-3-yl)benzamide
CAS:1253186-46-7
MF:C23H17F2N3O2
MW:405.4
EINECS:
Product Categories:
Mol File:1253186-46-7.mol
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- Structure
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- Chemical Properties
Boiling point 499.7±45.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
pka10.87±0.70(Predicted)
Safety Information
MSDS Information
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- Usage And Synthesis
DescriptionGSK-5503A is a novel selective CRAC channel blocker.
UsesGSK-5503A is a calcium-release activated calcium (CRAC) channel blocker. GSK-5503A effectively inhibits stromal interaction molecule 1 (STIM1) mediated Orai1 and Orai3 currents in vitro. GSK-5503A can be used for the research of asthma and allergic disorders[1].
References[1] Derler I, et al. The action of selective CRAC channel blockers is affected by the Orai pore geometry. Cell Calcium. 2013 Feb;53(2):139-51. DOI:10.1016/j.ceca.2012.11.005
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- Preparation Products And Raw materials
Tag:Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]-(1253186-46-7) Related Product Information
Benzamide, 2,6-difluoro-N-[1-[(2-phenoxyphenyl)methyl]-1H-pyrazol-3-yl]- GSK-7975A Pyr6 1H-Pyrazole, 3-[(1E)-2-(2,6-difluorophenyl)diazenyl]-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]- GS 283 2-Aminoethoxydiphenyl borate