2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester

2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester Basic information
Product Name:2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester
Synonyms:2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester;Relzomostat
CAS:2081078-92-2
MF:C24H36F2N2O5
MW:470.55
EINECS:
Product Categories:
Mol File:2081078-92-2.mol
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester Structure
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester Chemical Properties
Boiling point 535.4±50.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
pka5.78±0.20(Predicted)
Safety Information
MSDS Information
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester Usage And Synthesis
UsesRelzomostat is a methionine aminopeptidase 2 (MetAP2) inhibitor.Relzomostat may be useful for the research of obesity, type 2 diabetes, and other obesity-associated conditions[1].
References[1] Zahler, Robert; Vath, James E. Preparation of fumagillol spirocyclic and fused bicyclic compounds and their use as MetAP2 inhibitors. WO2017027687A1
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester Preparation Products And Raw materials
Tag:2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester(2081078-92-2) Related Product Information
2,6-Diazaspiro[3.3]heptane-2-carboxylic acid, 6-(2,2-difluoroethyl)-, (3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methyl-2-buten-1-yl)-2-oxiranyl]-1-oxaspiro[2.5]oct-6-yl ester ZGN-1061 LAF389 A-800141 (A800141) 5-(4-bromophenyl)-1H-1,2,3-triazole M-8891