Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester

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Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester Basic information
Product Name:Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester
Synonyms:Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester;ALR-38
CAS:241127-61-7
MF:C19H17NO4
MW:323.34
EINECS:
Product Categories:
Mol File:241127-61-7.mol
Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester Structure
Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester Chemical Properties
Boiling point 586.0±45.0 °C(Predicted)
density 1.355±0.06 g/cm3(Predicted)
pka10.11±0.50(Predicted)
Safety Information
MSDS Information
Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester Usage And Synthesis
UsesALR-38 is a 5-lipoxygenase (5-LOX) inhibitor (IC50: 1.1 μM) with anti-inflammatory activity. ALR-38 effectively reduces ROS levels in neutrophils[1].
References[1] Cerchia C et al. Identification of selective 5-LOX and FLAP inhibitors as novel anti-inflammatory agents by ligand-based virtual screening. Eur J Med Chem. 2023 Nov 8;263:115932. DOI:10.1016/j.ejmech.2023.115932
Benzoic acid, 4-[[(1,4-dihydroxy-2-naphthalenyl)methyl]amino]-, methyl ester Preparation Products And Raw materials
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