3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-

Request For Quotation
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Suppliers list
Company Name: Shanghai Lollane Biological Technology Co.,Ltd.  
Tel: 021-52996696，15000506266 15000506266
Email:
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 177-54423994 17754423994
Email: 2853530910@QQ.com
Company Name: Shanghai Chaolan Chemical Technology Center  
Tel: QQ：65489617 13301690235
Email: Sales@ATKchemical.com
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Basic information
Product Name:3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-
Synonyms:3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-;2-(1-((1H-Imidazo[4,5-b]pyridin-2-yl)methyl)piperidin-4-yl)-4-(benzofuran-2-yl)thiazole;BAY-179, 10 mM in DMSO;Complex 1 probe BAY-179;BAY-179 ，E1149
CAS:2764880-87-5
MF:C23H21N5OS
MW:415.51
EINECS:
Product Categories:
Mol File:2764880-87-5.mol
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Structure
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Chemical Properties
Boiling point 675.2±55.0 °C(Predicted)
density 1.367±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: 2mg/mL, clear (Warmed)
pka11.38±0.40(Predicted)
form Solid
color Off-white to light yellow
InChI1S/C23H21N5OS/c1-2-6-19-16(4-1)12-20(29-19)18-14-30-23(26-18)15-7-10-28(11-8-15)13-21-25-17-5-3-9-24-22(17)27-21/h1-6,9,12,14-15H,7-8,10-11,13H2,(H,24,25,27)
InChIKeyJOCPQSJABURDDD-UHFFFAOYSA-N
SMILESC12=C(C=CC=N2)NC(CN3CCC(CC3)C4=NC(C5=CC6=CC=CC=C6O5)=CS4)=N1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Usage And Synthesis
DescriptionBAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
UsesBAY-179 is a potent, selective, and species cross-reactive complex I inhibitor. BAY-179 shows IC50 values of 79 nM, 38 nM, 27 nM, and 47 nM for human, mouse, rat, and dog complex I, respectively[1].
References[1] Mowat J, et al. Identification of the Highly Active, Species Cross-Reactive Complex I Inhibitor BAY-179. ACS Med Chem Lett. 2022;13(3):348-357. Published 2022 Feb 18. DOI:10.1021/acsmedchemlett.1c00666
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- Preparation Products And Raw materials
Tag:3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]-(2764880-87-5) Related Product Information
3H-Imidazo[4,5-b]pyridine, 2-[[4-[4-(2-benzofuranyl)-2-thiazolyl]-1-piperidinyl]methyl]- (S)-BAY 73-6691 Bay 60-7550 Bay 87-2243 Butanoic acid, 2-[[3-cyano-2-(2′-fluoro-3′-methyl[1,1′-biphenyl]-4-yl)-1,7-naphthyridin-4-yl]amino]-, (2R)- BAY 11-7082