1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]-

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1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- manufacturers

  • MIF-IN-6
  • MIF-IN-6 pictures
  • $1520.00
  • 2026-05-11
  • CAS:2582758-61-8
  • Purity:
  • Supply Ability: 10g
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Basic information
Product Name:1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]-
Synonyms:1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]-;MIF-IN-6
CAS:2582758-61-8
MF:C18H13ClFN5O2
MW:385.78
EINECS:
Product Categories:
Mol File:2582758-61-8.mol
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Structure
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Chemical Properties
density 1.57±0.1 g/cm3(Predicted)
pka7.23±0.20(Predicted)
Safety Information
MSDS Information
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Usage And Synthesis
UsesMIF-IN-6 (compound 2d) is a potent macrophage migration inhibitory factor (MIF) inhibitor with an IC50 of 1.4 μM and a Ki value of 0.96 μM, respectively. MIF-IN-6 attenuates MIF-induced ERK phosphorylation and inhibits proliferation of A549 cells[1].
References[1] Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF). Eur J Med Chem. 2020;186:111849. DOI:10.1016/j.ejmech.2019.111849
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Preparation Products And Raw materials
Tag:1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]-(2582758-61-8) Related Product Information
1H-Indole-2-carboxamide, 5-chloro-N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- 1H-Indole-2-carboxamide, N-[[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]methyl]- Carebastine D-DTMIF-1-IN-1 4-Iodo-6-phenylpyrimidine Octanamide, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-N-[4-(7-hydroxy-2-oxo-2H-1,3-benzoxazin-3(4H)-yl)phenyl]-